FlyBase Allele Report: Dmel\Tm1[el4]

General Information

Symbol

Dmel\Tm1^el4

Species

D. melanogaster

Name

FlyBase ID

FBal0049225

Feature type

allele

Associated gene

Dmel\Tm1

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Erdelyi et al., 1995)

Progenitor genotype

Tm1^gs1

(Erdelyi et al., 1995)

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy

(Li and Gao, 2003)

abnormal neuroanatomy (with Tm1^S130510)

(Li and Gao, 2003)

lethal | recessive

(Erdelyi et al., 1995)

sterile | germline clone | maternal effect

(Erdelyi et al., 1995)

Phenotype Manifest In

dendritic arborising neuron & dendrite (with Tm1^S130510)

(Li and Gao, 2003)

dorsal multidendritic neuron ddaE & dendrite

(Li and Gao, 2003)

dorsal multidendritic neuron ddaE & dendrite (with Tm1^S130510)

(Li and Gao, 2003)

Detailed Description

Statement

Reference

The dendrites of dorsal cluster dendritic arborization (DA) neurons and ddaE neurons overextend in Tm1^S130510/Tm1^el4 transheterozygotes. This phenotype also occurs in Tm1^el4 homozygotes. The amount and length of lateral branches that extend from the dorsal dendrites is greater in Tm1^S130510/Tm1^el4 transheterozygotes than in wild-type embryos.

(Li and Gao, 2003)

Mosaic egg chambers are viable and produce the germ cell less phenotype of Tm1^gs1 and develop into sterile adults (embryos exhibit abdominal defects).

(Erdelyi et al., 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Tm1^el4/Tm1^S130510 has abnormal neuroanatomy phenotype, enhanceable by stan[+]/stan⁵¹

(Li and Gao, 2003)

Tm1^el4/Tm1^eg9, osk¹ has some die during embryonic stage | maternal effect | recessive phenotype, enhanceable by E(To)10¹⁰

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has some die during embryonic stage | maternal effect | recessive phenotype, enhanceable by E(To)12¹²

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has some die during embryonic stage | maternal effect | recessive phenotype, enhanceable by Rab11^ETo3

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has some die during embryonic stage | maternal effect | recessive phenotype, enhanceable by mago^ETo2

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has some die during embryonic stage | maternal effect | recessive phenotype, enhanceable by vas^ETo14

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has some die during embryonic stage | maternal effect | recessive phenotype, enhanceable by E(To)13¹³

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has some die during embryonic stage | maternal effect | recessive phenotype, enhanceable by E(To)1¹

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has some die during embryonic stage | maternal effect | recessive phenotype, enhanceable by E(To)4⁴

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has some die during embryonic stage | maternal effect | recessive phenotype, enhanceable by E(To)5⁵

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has some die during embryonic stage | maternal effect | recessive phenotype, enhanceable by E(To)6⁶

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has some die during embryonic stage | maternal effect | recessive phenotype, enhanceable by E(To)8⁸

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has some die during embryonic stage | maternal effect | recessive phenotype, enhanceable by E(To)9⁹

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has some die during embryonic stage | maternal effect | recessive phenotype, enhanceable by Rab11^ETo11

(Jankovics et al., 2001)

Other

Statement

Reference

Tm1^el4/Tm1^eg9, osk¹ has some die during embryonic stage | recessive | recessive | maternal effect phenotype

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk^ETo7/osk¹ has some die during embryonic stage | maternal effect phenotype

(Jankovics et al., 2001)

Phenotype Manifest In

Enhanced by

Statement

Reference

Tm1^el4/Tm1^S130510 has dorsal multidendritic neuron ddaE & dendrite phenotype, enhanceable by stan[+]/stan⁵¹

(Li and Gao, 2003)

Tm1^el4/Tm1^eg9, osk¹ has embryonic abdominal segment phenotype, enhanceable by E(To)10¹⁰/E(To)10[+]

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has embryonic abdominal segment phenotype, enhanceable by E(To)12¹²/E(To)12[+]

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has embryonic/first instar larval cuticle phenotype, enhanceable by E(To)12¹²/E(To)12[+]

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has embryonic abdominal segment phenotype, enhanceable by E(To)13[+]/E(To)13¹³

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has embryonic abdominal segment phenotype, enhanceable by E(To)1¹/E(To)1[+]

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has embryonic abdominal segment phenotype, enhanceable by E(To)4[+]/E(To)4⁴

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has embryonic abdominal segment phenotype, enhanceable by E(To)5⁵/E(To)5[+]

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has embryonic/first instar larval cuticle phenotype, enhanceable by E(To)5⁵/E(To)5[+]

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has embryonic abdominal segment phenotype, enhanceable by E(To)6⁶/E(To)6[+]

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has embryonic abdominal segment phenotype, enhanceable by E(To)8[+]/E(To)8⁸

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has embryonic abdominal segment phenotype, enhanceable by E(To)9[+]/E(To)9⁹

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has embryonic abdominal segment phenotype, enhanceable by Rab11^ETo11/Rab11[+]

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has embryonic abdominal segment phenotype, enhanceable by Rab11[+]/Rab11^ETo3

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has embryonic abdominal segment phenotype, enhanceable by mago^ETo2/mago[+]

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has embryonic abdominal segment phenotype, enhanceable by vas^ETo14/vas[+]

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk[+]/osk¹ has embryonic abdominal segment phenotype, enhanceable by E(To)10¹⁰/E(To)10[+]

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk[+]/osk¹ has embryonic abdominal segment phenotype, enhanceable by E(To)12¹²/E(To)12[+]

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk[+]/osk¹ has embryonic/first instar larval cuticle phenotype, enhanceable by E(To)12¹²/E(To)12[+]

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9 has embryonic/first instar larval cuticle phenotype, enhanceable by osk[+]/osk¹/E(To)12¹²/E(To)12[+]

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk[+]/osk¹ has embryonic abdominal segment phenotype, enhanceable by E(To)13[+]/E(To)13¹³

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk[+]/osk¹ has embryonic abdominal segment phenotype, enhanceable by E(To)1¹/E(To)1[+]

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk[+]/osk¹ has embryonic abdominal segment phenotype, enhanceable by E(To)4[+]/E(To)4⁴

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk[+]/osk¹ has embryonic abdominal segment phenotype, enhanceable by E(To)5⁵/E(To)5[+]

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk[+]/osk¹ has embryonic/first instar larval cuticle phenotype, enhanceable by E(To)5⁵/E(To)5[+]

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk[+]/osk¹ has embryonic abdominal segment phenotype, enhanceable by E(To)6⁶/E(To)6[+]

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk[+]/osk¹ has embryonic abdominal segment phenotype, enhanceable by E(To)8[+]/E(To)8⁸

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk[+]/osk¹ has embryonic abdominal segment phenotype, enhanceable by E(To)9[+]/E(To)9⁹

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk[+]/osk¹ has embryonic abdominal segment phenotype, enhanceable by Rab11^ETo11/Rab11[+]

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk[+]/osk¹ has embryonic abdominal segment phenotype, enhanceable by Rab11[+]/Rab11^ETo3

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk[+]/osk¹ has embryonic abdominal segment phenotype, enhanceable by mago^ETo2/mago[+]

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk[+]/osk¹ has embryonic abdominal segment phenotype, enhanceable by vas^ETo14/vas[+]

(Jankovics et al., 2001)

Other

Statement

Reference

Tm1^el4/Tm1^eg9, osk¹ has embryonic abdominal segment phenotype

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk¹ has embryonic/first instar larval cuticle phenotype

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk^ETo7/osk¹ has embryonic abdominal segment phenotype

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk[+]/osk¹ has embryonic abdominal segment phenotype

(Jankovics et al., 2001)

Tm1^el4/Tm1^eg9, osk[+]/osk¹ has embryonic/first instar larval cuticle phenotype

(Jankovics et al., 2001)

Additional Comments

Genetic Interactions

Statement

Reference

Embryos that are Tm1^S130510/Tm1^el4 transheterozygotes in a stan⁵¹/+ background have an enhanced dendritic overextension phenotype in ddaE neurons.

(Li and Gao, 2003)

66% of eggs derived from Tm1^eg9 +/Tm1^el4 osk¹ females do not develop into viable larvae. In 44% of the dead eggs, embryogenesis does not commence, or is terminated before cuticle formation, while 56% of the dead eggs have a characteristic "posterior group" phenotype with missing abdominal segments.

(Jankovics et al., 2001)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Tm1^el4

TmII^el4

(Jankovics et al., 2001)

Name Synonyms

Secondary FlyBase IDs

References (3)

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