FB2024_03 , released June 25, 2024
Allele: Dmel\srG11
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General Information
Symbol
Dmel\srG11
Species
D. melanogaster
Name
FlyBase ID
FBal0050558
Feature type
allele
Associated gene
Dmel\sr
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Frommer et al., 1996)
Progenitor genotype
sr03999
(Frommer et al., 1996)
Cytology
Description

2074bp deletion of genomic DNA due to imprecise deletion of the P{PZ} insertion of sr03999.

(Frommer et al., 1996)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      A reduced number of cells are found in the dorsal and ganglionic branches, and the dorsal trunk branches fail to fuse though, tracheal migration is generally normal in homozygous mutants and terminal cell differentiation is not affected.

      (Dorfman et al., 2002)

      Homozygous embryos have a normal somatic muscle pattern and generally hatch, although they do not develop into adult flies. Homozygous srG11 embryos that are expressing srScer\UAS.cBa under the control of Scer\GAL4en-e16E show a severe disruption of the somatic muscle pattern, especially that of the lateral transverse muscles.

      (Becker et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      sr[+]/srG11 is an enhancer of indirect flight muscle cell phenotype of ap4

      (Ghazi et al., 2000)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      srG11
      Name Synonyms
      Secondary FlyBase IDs
        References (4)