FB2024_03 , released June 25, 2024
Allele: Dmel\wunCE
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General Information
Symbol
Dmel\wunCE
Species
D. melanogaster
Name
FlyBase ID
FBal0050885
Feature type
allele
Associated gene
Dmel\wun
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
    Nature of the Allele
    Allele class

    loss of function allele

    (Zhang et al., 1997)
    Mutagen
    Progenitor genotype
    Caused by aberration
    Ab(2;?)wunCE
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Male germ cells that are mis-localised (not within the gonad) do not proliferate in mutant embryos.

        (Wawersik et al., 2005)

        Hemizygotes are temperature sensitive semi-lethal. wunCE/Df(2R)wun-GL females are often agametic. Germ cells fail to cluster on the dorsal posterior surface of the posterior midgut primordium.

        (Zhang et al., 1996)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The pole cell death phenotype of embryos from wun2N14/Df(2R)w45-19g mothers is partially suppressed by zygotic wunCE/Df(2R)w45-19g, although proper migration of the pole cells is not rescued in these embryos (Note wunCE/Df(2R)w45-19g vs wunCE/+ embryos not indpendently scoreable, but in a 1:1 population of each, 50% had a less severe cell death phenotype than wun+ embryos from wun2N14/Df(2R)w45-19g mothers. These were assumed to be wunCE/Df(2R)w45-19g rather than wunCE/+).

        (Hanyu-Nakamura et al., 2004)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Fails to complement

        wunEMS9

        (Renault et al., 2004)
        Rescued by

        wunCE is rescued by wun+tNN

        (Zhang et al., 1997)
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer

        Induced on: Df(2R)44CE.

        (Zhang et al., 1996)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        wunCE
        (Stepanik et al., 2016, Sano et al., 2005, Renault et al., 2004)
        wunce
        (Jones and Macdonald, 2015)
        wunenCE
        (Wawersik et al., 2005)
        Name Synonyms
        Secondary FlyBase IDs
          References (9)