FB2024_03 , released June 25, 2024
Allele: Dmel\tkvTAJ3
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General Information
Symbol
Dmel\tkvTAJ3
Species
D. melanogaster
Name
FlyBase ID
FBal0051061
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Associated Insertion(s)
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

tkvTAJ3 flies form ectopic wing vein material between veins L3 and L4.

Blistered and reduced wing phenotype.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference

tkvTAJ3 has visible phenotype, suppressible by Ack10b/Ack10b

Phenotype Manifest In
Suppressed by
Statement
Reference

tkvTAJ3 has wing vein | ectopic phenotype, suppressible by Ack10b/Ack10b

tkvTAJ3 has phenotype, suppressible by shnunspecified/shn[+]

tkvTAJ3 has wing phenotype, suppressible by Mad12/Mad[+]

tkvTAJ3 has wing phenotype, suppressible by Mad[+]/Mad1

tkvTAJ3 has wing phenotype, suppressible by Mad[+]/Mad6

tkvTAJ3 has wing phenotype, suppressible by Mad[+]/MadP-23D

tkvTAJ3 has wing phenotype, suppressible by Df(2L)C28

NOT suppressed by
Statement
Reference

tkvTAJ3 has wing phenotype, non-suppressible by putunspecified

Suppressor of
Statement
Reference
NOT Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

The ectopic wing vein phenotype seen in tkvTAJ3 flies is significantly suppressed by Ack10b/Ack10b.

tkvTAJ3 partially rescues the dorsal closure defect caused by expression of Rac1N17.Scer\UAS under the control of Scer\GAL4hs.PB. tkvTAJ3 has no effect on the phenotype caused by expression of Cdc42N17.Scer\UAS under the control of Scer\GAL4hs.PB.

Wing phenotype is completely suppressed by Df(2L)C28, almost completely suppressed by Mad1 or Mad6 and weakly suppressed by Mad12 or MadP-23D.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
tkvTAJ3
Name Synonyms
Secondary FlyBase IDs
    References (3)