FlyBase Allele Report: Dmel\pnr[V1]

General Information

Symbol

Dmel\pnr^V1

Species

D. melanogaster

Name

FlyBase ID

FBal0051273

Feature type

allele

Associated gene

Dmel\pnr

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

gain of function allele

hypomorphic allele - genetic evidence

Mutagen

spontaneous

Nature of the Allele

Allele class

gain of function allele

(Calleja et al., 1996)

hypomorphic allele - genetic evidence

(Heitzler et al., 1996)

Mutagen

spontaneous

(Heitzler et al., 1996)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable

(Heitzler et al., 1996)

visible

(Fromental-Ramain et al., 2008)

visible (with pnr^MD237)

(Escudero et al., 2005)

Phenotype Manifest In

Detailed Description

Statement

Reference

Homozygous pnr^V1 mutants lack dorsocentral bristles.

(Fromental-Ramain et al., 2008)

pnr^MD237/pnr^V1 flies show loss of dorsocentral and scutellar macrochaetae.

(Escudero et al., 2005)

pnr^V1/pnr^VX1 mutants show abnormal muscle attachments. The dorsal medial muscle (DLM)s appear as a single fibre that resembles the lateral oblique dorsal muscle (DVM III) in its orientation.

(Ghazi et al., 2003)

In pnr^V1/pnr^VX1 mutants the wg-dependent dorsocentral bristles and scutellar bristles are missing.

(Calleja et al., 1996)

In(3R)iab6^G/pnr^V1 flies show a severe cleft, head defects and split tergites. Heterozygotes with Df(3R)sbd45 lack bristles and occasionally show head defects.

(Heitzler et al., 1996)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

pnr^MD237/pnr^V1 has visible phenotype, enhanceable by Scer\GAL4^pnr-MD237/chn^RNAi.UAS

(Escudero et al., 2005)

Phenotype Manifest In

Enhanced by

Statement

Reference

pnr^MD237/pnr^V1 has dorsocentral bristle phenotype, enhanceable by Scer\GAL4^pnr-MD237/chn^RNAi.UAS

(Escudero et al., 2005)

pnr^MD237/pnr^V1 has scutellar bristle phenotype, enhanceable by Scer\GAL4^pnr-MD237/chn^RNAi.UAS

(Escudero et al., 2005)

NOT Enhancer of

Statement

Reference

pnr[+]/pnr^V1 is a non-enhancer of wing margin phenotype of Bx²

(Bronstein et al., 2010)

NOT Suppressor of

Statement

Reference

pnr[+]/pnr^V1 is a non-suppressor of wing margin phenotype of Bx²

(Bronstein et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

36553

kar² ry⁵⁰⁶ pnr^V1/TM6C, Sb¹ Tb¹

Notes on Origin

Discoverer

Comments

Class 1 pnr allele: viable recessive allele.

(Heitzler et al., 1996)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

pnr^V1

(Bronstein et al., 2010, Fromental-Ramain et al., 2010, Fromental-Ramain et al., 2008)

pnr^v1

(Herrero et al., 2014, Benito-Sipos et al., 2010, Simpson, 1997)

Name Synonyms

Secondary FlyBase IDs

References (12)

Report Sections

Open Close