FB2024_03 , released June 25, 2024
Allele: Dmel\pn77C33
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General Information
Symbol
Dmel\pn77C33
Species
D. melanogaster
Name
FlyBase ID
FBal0056300
Feature type
allele
Associated gene
Dmel\pn
Associated Insertion(s)
P{}pn77C33
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Timmons and Shearn, 1996)
Progenitor genotype
Associated Insertion(s)
P{}pn77C33
Cytology
Description

P-element insertion within codon 62, provides an in-frame stop codon 4 amino acids into the inserted sequence.

(Timmons and Shearn, 1996)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous larvae develop normally.

      (Timmons et al., 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Lethality of awdK/+, pn77C33 double mutants is not due to an inadequate level of awd NDP kinase activity.

      (Timmons et al., 1995)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      pn77C33 is rescued by pnhs.3

      (Timmons and Shearn, 1996)
      Not rescued by

      pn77C33 is not rescued by pnhs.4

      (Timmons and Shearn, 1996)
      Comments

      pnhs.4 fails to rescue the lethal interaction of pn77C33 with awdK. pnhs.3 does rescue the lethality (with or without heat shock) and male progeny are recovered. Eye colour of P{HS-PN+4} transformants remains pn even after several heat pulses, P{HS-PN+3} transformants (without heat shock or with one or numerous heat shocks) exhibit wild-type colouration.

      (Timmons and Shearn, 1996)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      M. Green.

      (Timmons and Shearn, 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      pn77C33
      Name Synonyms
      Secondary FlyBase IDs
        References (2)