FB2024_03 , released June 25, 2024
Allele: Dmel\nanos+t5.7
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General Information
Symbol
Dmel\nanos+t5.7
Species
D. melanogaster
Name
FlyBase ID
FBal0056423
Feature type
allele
Associated gene
Dmel\nanos
Associated Insertion(s)
Carried in Construct
P{nanos+}
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Dahanukar and Wharton, 1996)
wild_type
(Dahanukar and Wharton, 1996)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Dahanukar and Wharton, 1996)
wild_type
(Dahanukar and Wharton, 1996)
Mutagen
in vitro construct
(Dahanukar and Wharton, 1996)
Progenitor genotype
Carried in construct
P{nanos+}
Cytology
Description

Included within a 5.7kb EcoRI-DraIII genomic fragment.

(Dahanukar and Wharton, 1996)
Allele components
Component
Use(s)
Regulatory region(s)
nanos
Encoded product / tool
nanos
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
3R:19,154,879..19,160,361 [+]
Linked to:
EcoRI-DraIII restriction fragment
Comment:

Position of restriction fragment on reference sequence inferred by FlyBase curator.

(Dahanukar and Wharton, 1996)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Only about 55% of the progeny of hb15; nosBN germ-line clone mothers mated to wild-type fathers hatch into first instar larvae, but most of those that hatch make it to adulthood (42% of all progeny). This embryonic lethality is rescued by nos+t5.7.

      (Deshpande et al., 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      nanos+t5.7 rescues nanos18

      (Verrotti and Wharton, 2000)

      nanos+t5.7 rescues nanosBN

      (Verrotti and Wharton, 2000)
      Comments

      Rescues the abdominal segmentation defects seen in embryos derived from nosBN females. Rescues the oogenesis defects seen in nos18 hemizygous females; females lay fertilised eggs and have ovaries of normal size.

      (Verrotti and Wharton, 2000)

      Rescues the maternal nos mutant phenotype.

      (Dahanukar and Wharton, 1996)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      nanos+t5.7
      nos+t5.7
      Name Synonyms
      Secondary FlyBase IDs
        References (3)