FB2024_03 , released June 25, 2024
Allele: Dmel\mtsk09822
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General Information
Symbol
Dmel\mtsk09822
Species
D. melanogaster
Name
FlyBase ID
FBal0061019
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Associated Insertion(s)
Cytology
Description

P{lacW} insertion within 5' flanking sequences 251bp upstream of the initiating ATG.

Allele components
Component
Use(s)
Inserted element
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Embryos die around the time of cellularisation exhibiting over-condensed chromatin and a block in mitosis between prophase and the initiation of anaphase. Multiple centrosomes are visible surrounding the DNA of each cell. When embryos arrest just prior to cellularisation, disorganised elongated arrays of microtubules radiates from centrosomes in all directions but they are rarely associated with any DNA.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Viability of reversion strains demonstrates the lethality is due to the presence of the P{lacW} element.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
Reported As
Symbol Synonym
l(2)k09822
l(2)k09822k09822
mtsk09822
Name Synonyms
Secondary FlyBase IDs
    References (4)