FB2024_03 , released June 25, 2024
Allele: Scer\GAL4Alp4-c507
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General Information
Symbol
Scer\GAL4Alp4-c507
Species
S. cerevisiae
Name
FlyBase ID
FBal0061883
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
P{GawB}Alp4c507
Carried in Construct
Also Known As
c507, c507-Gal4
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Sozen et al., 1997)
Progenitor genotype
Associated Insertion(s)
P{GawB}Alp4c507
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{GawB}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      adult ellipsoid body ring neuron R3
      (Renn et al., 1999)
      adult stage
      adult ellipsoid body ring neuron R3
      (Martín-Peña et al., 2014, Yang et al., 2000, Renn et al., 1999)
      Malpighian tubule
      (Yang et al., 2000)
      ellipsoid body
      (Yang et al., 2000)
      adult ellipsoid body ring neuron R4 | distal | subset
      (Renn et al., 1999)
      adult ellipsoid body ring neuron R4
      (Cavanaugh et al., 2014, Yang et al., 2000)
      ellipsoid body | restricted
      (Renn et al., 1999)
      ureter
      (Yang et al., 2000, Sozen et al., 1997)
      large field neuron | subset
      (Renn et al., 1999)
      adult pars intercerebralis | restricted
      (Cavanaugh et al., 2014)
      adult ellipsoid body ring neuron R1
      (Martín-Peña et al., 2014)
      adult ellipsoid body ring neuron R2
      (Martín-Peña et al., 2014)
      adult ellipsoid body ring neuron R4m
      (Martín-Peña et al., 2014)
      adult ellipsoid body ring neuron R3 | subset
      (Bridi et al., 2019)
      adult ellipsoid body ring neuron R4d | subset
      (Bridi et al., 2019)
      lower segment of Malpighian tubule
      (Yang et al., 2000, Sozen et al., 1997)
      Additional Information
      Statement
      Reference

      Drives expression in ring neurons R3 and R4 in the ellipsoid body, and the Malpighian tubule lower segment and ureter.

      (FlyBase Curators, 2017)

      ScerGAL4Alp4-c507 drives expression in about 33 ring neurons at 7-8 days of age.

      (Martín-Peña et al., 2014)

      Expression is limited to just a few cell types. In the brain, expression is found in the ring neurons of the ellipsoid body, specifically in the R3 and R4 morphological subtypes. In addition, expression is observed in the lower section and ureter of the Malpighian tubules.

      (Yang et al., 2000)

      Adult expression is observed in R3 ring neurons and in the subset of R4 neurons that arborize in the distal part of the ellipsoid body.

      (Renn et al., 1999)

      In adults, expressed in the Malpighian tubules; expression confined to the lower segment of Malpighian tubule and the ureter. Expression is not observed in the initial or main segements of the Malpighian tubule. Marks the lower tubule as a separate domain of the main segment.

      (Sozen et al., 1997)
       
      Marker for
      adult ellipsoid body ring neuron R3
      (Renn et al., 1999)
      adult ellipsoid body ring neuron R4d
      (Renn et al., 1999)
      ellipsoid body
      (Renn et al., 1999)
      lower segment of Malpighian tubule
      (Sozen et al., 1997)
      Reflects expression of
      Alp4
      (Cavanaugh et al., 2014, Martín-Peña et al., 2014, Yang et al., 2000)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      NOT Enhanced by
      NOT suppressed by
      Enhancer of
      NOT Enhancer of
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      GAL4anon-l-c507
      GAL4c507
      Scer\GAL4Alp4-c507
      Scer\GAL4Aph-4-c507
      Scer\GAL4anon-l-c507
      Scer\GAL4l(3)03670-c507
      Name Synonyms
      Secondary FlyBase IDs
        References (28)