FB2024_03 , released June 25, 2024
Allele: Scer\GAL4Mz840
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General Information
Symbol
Scer\GAL4Mz840
Species
S. cerevisiae
Name
FlyBase ID
FBal0061887
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
P{GawB}Mz840
Carried in Construct
Also Known As
MZ840, Mz840-GAL4
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Ito et al., 1995)
Progenitor genotype
Associated Insertion(s)
P{GawB}Mz840
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{GawB}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 16
      midline glial cell
      (Ito et al., 1995)
      embryonic longitudinal glial cell
      (Ito et al., 1995)
      embryonic/larval cell body glial cell
      (Ito et al., 1995)
      first instar larval stage
      glial cell of embryonic/larval central nervous system
      (Ito et al., 1995)
      embryonic/larval central nervous system | restricted
      (Ito et al., 1995)
      adult stage
      mushroom body vertical lobe arborizing neuron 1
      (Zhang et al., 2022, Flybrain Neuron Database et al., 2018.6.28, Tanaka et al., 2008)
      mushroom body alpha' lobe slice 2
      (Tanaka et al., 2008)
      mushroom body alpha' middle layer
      (Tanaka et al., 2008)
      mushroom body alpha' anterior-posterior layer
      (Tanaka et al., 2008)
      mushroom body alpha lobe slice 1
      (Tanaka et al., 2008)
      mushroom body alpha lobe posterior layer
      (Tanaka et al., 2008)
      mushroom body alpha lobe surface layer
      (Tanaka et al., 2008)
      mushroom body alpha lobe core layer
      (Tanaka et al., 2008)
      fan-shaped body | restricted
      (Tanaka et al., 2008)
      dopaminergic PPL1 neuron | subset
      (Aso et al., 2012)
      mushroom body vertical lobe arborizing neuron 1 | subset
      (Aso et al., 2012)
      adult neuron | subset of adult brain
      (Zhang et al., 2022)
      Additional Information
      Statement
      Reference

      ScerGAL4Mz840 drives expression in one dopaminergic PPL1 neuron (one MB-V1 neuron).

      (Aso et al., 2012)

      Expression in glial cells not exclusive, expressed in other tissues as well.

      (Ito et al., 1995)
       
      Marker for
      mushroom body vertical lobe arborizing neuron 1
      (Tanaka et al., 2008)
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Inhibition (using shi1.UAS at 32[o]C) of Scer\GAL4Mz840 cells in adults does not affect startle-induced climbing behavior, compared to controls.

      Thermogenetic activation (using TrpA1UAS.(B).cKa at 32[o]C) of Scer\GAL4Mz840 cells in adults significantly reduces startle-induced climbing behavior, compared to controls.

      (Sun et al., 2018)

      Thermogenetic activation (using TrpA1UAS.(B).cKa at 30[o]C) of Scer\GAL4Mz840 cells in adults, in combination with a paired odor, does not significantly affect 2-min olfactory memory, compared to controls.

      (Aso et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      sbbUAS.cYa/Scer\GAL4Mz840 fails to rescue sbb03432

      (Suster et al., 2004)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      GAL4Mz840
      Scer\GAL4Mz840
      Name Synonyms
      Secondary FlyBase IDs
        References (11)