FlyBase Allele Report: Scer\GAL4[Mz709]

General Information

Symbol

Scer\GAL4^Mz709

Species

S. cerevisiae

Name

FlyBase ID

FBal0061890

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

P{GawB}Mz709

Carried in Construct

Also Known As

mZ0709-Gal4, mz709-GAL4, mz0709, MZ709

Allele class

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

Mutagen

Delta2-3 transposase

(Ito et al., 1995)

Progenitor genotype

Associated Insertion(s)

P{GawB}Mz709

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GawB}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 16 -- 17

embryonic longitudinal glial cell

(Ito et al., 1995)

intersegmental nerve root glial cell

(Ito et al., 1995)

larval channel glial cell

(Ito et al., 1995)

presumptive embryonic/larval central nervous system | restricted

(Ito et al., 1995)

segmental nerve root glial cell

(Ito et al., 1995)

first instar larval stage

glial cell of embryonic/larval central nervous system

(Ito et al., 1995)

embryonic/larval central nervous system | restricted

(Ito et al., 1995)

adult stage

adult ensheathing glial cell of adult antennal lobe

(Doherty et al., 2009)

adult ensheathing glial cell of adult mushroom body

(Doherty et al., 2009)

adult lamina marginal glial cell

(Stenesen et al., 2019)

adult lamina satellite glial cell

(Stenesen et al., 2019)

ensheathing glial cell

(Lee et al., 2019)

adult ensheathing glial cell

(Dutta et al., 2016)

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult lamina satellite glial cell

(Chaturvedi et al., 2014)

Additional Information

Statement

Reference

ScerGAL4^Mz709 drives expression in marginal and satellite glial cells in the adult retina.

(Stenesen et al., 2019)

ScerGAL4^Mz709 drives expression in ensheathing glial cells.

(Lee et al., 2019)

Drives expression in ensheathing glial cells.

(FlyBase Curators, 2017)

Expression in glial cells not exclusive, expressed in other tissues as well.

(Ito et al., 1995)

Marker for

adult ensheathing glial cell

(Doherty et al., 2009)

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | adult stage, with Hsap\GFAP^R79H.UAS

(Wang et al., 2015)

abnormal neuroanatomy | adult stage, with sws^GD3277

(Dutta et al., 2016)

abnormal neuroanatomy | heat sensitive, with shi^1.UAS

(Kazama et al., 2011)

abnormal neurophysiology, with Inx2^JF02446

(Chaturvedi et al., 2014)

abnormal phototaxis | adult stage, with sws^GD3277

(Dutta et al., 2016)

abnormal sleep, with Eaat2^HMS01998

(Stahl et al., 2018)

abnormal sleep, with shi^ts.UAS.cUa

(Stahl et al., 2018)

abnormal visual behavior, with Inx2^JF02446

(Chaturvedi et al., 2014)

bang sensitive, with kcc^HMS01058

(Rusan et al., 2014)

paralytic, with kcc^HMS01058

(Rusan et al., 2014)

viable, with Acox1^N250S.UAS

(Chung et al., 2020)

Phenotype Manifest In

adult brain subperineurial glial cell, with sws^GD3277

(Dutta et al., 2016)

adult CNS glial cell, with Hsap\GFAP^R79H.UAS

(Wang et al., 2015)

adult ensheathing glial cell, with drpr^RNAi.UAS

(Doherty et al., 2009)

adult ensheathing glial cell, with Shark^RNAi.UAS.WIZ

(Doherty et al., 2009)

adult ensheathing glial cell, with sws^GD3277

(Dutta et al., 2016)

adult ensheathing glial cell | heat sensitive, with shi^ts.UAS.cUa

(Doherty et al., 2009)

adult optic lobe, with sws^GD3277

(Dutta et al., 2016)

cell body rind of adult lamina | adult stage, with sws^GD3277

(Dutta et al., 2016)

glial cell | heat sensitive, with shi^1.UAS

(Kazama et al., 2011)

lobula | adult stage, with sws^GD3277

(Dutta et al., 2016)

medulla, with sws^GD3277

(Dutta et al., 2016)

photoreceptor neuron, with Inx2^JF02446

(Chaturvedi et al., 2014)

synaptic vesicle, with Inx2^JF02446

(Chaturvedi et al., 2014)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Rnor\Stk39^UAS.cLa/Scer\GAL4^Mz709 is a suppressor of lethal phenotype of fray^r1

(Leiserson et al., 2000)

Phenotype Manifest In

Suppressor of

Statement

Reference

Rnor\Stk39^UAS.cLa/Scer\GAL4^Mz709 is a suppressor of embryonic/larval peripheral nervous system phenotype of fray^r1

(Leiserson et al., 2000)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

fray^UAS.cLa/Scer\GAL4^Mz709 rescues fray^r1

(Leiserson et al., 2000)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

GAL4^Mz709

Scer\GAL4^Mz709

Name Synonyms

Secondary FlyBase IDs

References (35)

Report Sections