FB2024_03 , released June 25, 2024
Allele: Dmel\stckunspecified
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General Information
Symbol
Dmel\stckunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0062422
Feature type
allele
Associated gene
Dmel\stck
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
(Prout et al., 1997)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      More than 85% of hemizygous embryos die. Those larvae that survive are significantly shorter than normal, are nearly immobile and die within 24 hours of hatching.

      (Clark et al., 2003)

      Homozygotes die as early larvae. Homozygous clones in the wing produce discrete, round blisters of variable size. These blisters can be located anywhere on the wing. Wing venation is normal. Homozygous embryos show excessive contractions of the segmental muscles just before hatching. Hatched larvae fail to grow.

      (Prout et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      stck[+]/stckunspecified is an enhancer of visible | recessive phenotype of mys8

      (Prout et al., 1997)

      stck[+]/stckunspecified is an enhancer of visible | recessive phenotype of mysb9

      (Prout et al., 1997)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      stck[+]/stckunspecified is an enhancer of wing phenotype of mys8

      (Prout et al., 1997)

      stck[+]/stckunspecified is an enhancer of wing phenotype of mysb9

      (Prout et al., 1997)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Shows a weak genetic interaction with mys8 and mysb9; the frequency of held-out wings but not the frequency of blisters in mys8 or mysb9 single hemizygotes is increased if they are also heterozygous for stckunspecified.

      (Prout et al., 1997)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      stckunspecified is rescued by stck+tCa

      (Clark et al., 2003)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      stckunspecified
      unspecified
      (Prout et al., 1997)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)