FlyBase Allele Report: Dmel\mirr[SaiD3]

General Information

Symbol

Dmel\mirr^SaiD3

Species

D. melanogaster

Name

FlyBase ID

FBal0063874

Feature type

allele

Associated gene

Dmel\mirr

Associated Insertion(s)

Carried in Construct

Also Known As

mirr^D3

Key Links

Allele class

loss of function allele

Mutagen

Nature of the Allele

Allele class

loss of function allele

(Carpenter, 1997.9.12)

Mutagen

Progenitor genotype

Caused by aberration

In(3L)D³

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Yang et al., 1999, Carpenter, 1997.9.12)

Phenotype Manifest In

antennal disc

(Yang et al., 1999)

eye | dorsal | posterior

(Yang et al., 1999)

Detailed Description

Statement

Reference

Duplicated antennae are frequently observed in the eye-antennal discs of mirr^X52/mirr^SaiD3 animals. Escapers that survive to adulthood show a protrusion in the dorsal posterior region of the eye.

(Yang et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

mirr^SaiD3 is a suppressor of eye phenotype of Scer\GAL4^GMR.PS, caz^KK107486

(Shimamura et al., 2014)

mirr^SaiD3 is a suppressor of ommatidium phenotype of Scer\GAL4^GMR.PS, caz^KK107486

(Shimamura et al., 2014)

mirr^SaiD3 is a suppressor of interommatidial bristle phenotype of Scer\GAL4^GMR.PS, caz^KK107486

(Shimamura et al., 2014)

mirr^SaiD3 is a suppressor of cone cell phenotype of Scer\GAL4^GMR.PS, caz^KK107486

(Shimamura et al., 2014)

Additional Comments

Genetic Interactions

Statement

Reference

A mirr^SaiD3 background suppresses the rough eye phenotype induced by expression of caz^KK107486.

(Shimamura et al., 2014)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially complements

mirr^DH-1

(Carpenter, 1997.9.12)

Fails to complement

(Carpenter, 1999)

(Carpenter, 1999)

(Carpenter, 1999)

(Carpenter, 1999)

(Carpenter, 1997.9.12)

mirr^Sai1

(Carpenter, 1997.9.12)

Comments

The allele of mirr on In(3L)D³ (mirr^SaiD3) is phenotypically distinct from that on In(3L)D (mirr^SaiD1) as judged by viability of heterozygotes with the hypomorphic mirr^DH-1.

(Carpenter, 1997.9.12)

Images (0)

Mutant

Wild-type

Stocks (4)

Bloomington

4560

In(2L)Cy, In(2R)Cy, Duox^Cy speck²/l(2)*^*; fs(3)A1^1-256/In(3L)D³, mirr^SaiD3 D³

Kyoto

107705

sens^Ly-1/In(3L)D³, mirr^SaiD3 D³

105966