FB2024_03 , released June 25, 2024
Allele: Dmel\HC6.hs
Open Close
General Information
Symbol
Dmel\HC6.hs
Species
D. melanogaster
Name
FlyBase ID
FBal0066049
Feature type
allele
Associated gene
Dmel\H
Associated Insertion(s)
Carried in Construct
P{hs-H.C6}
Key Links
Transgenic product class
inframe_deletion
(Maier et al., 1997)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Maier et al., 1997)
Mutagen
in vitro construct
(Maier et al., 1997)
Progenitor genotype
Hhs.PM
(Maier et al., 1997)
Carried in construct
P{hs-H.C6}
Cytology
Description

Internal deletion of a 115bp SpeI fragment (between 3437 and 3552, 3' end deletion of 15 amino acids).

(Maier et al., 1997)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
H
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heat shock induced expression produces wild-type flies.

      (Morel et al., 2001)

      Heat induced expression causes few bristle duplications and socket to shaft transformations.

      (Maier et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Enhanced by
      Statement
      Reference

      HC6.hs has phenotype, non-enhanceable by Su(H)hs.PS

      (Morel et al., 2001)
      Suppressor of
      Statement
      Reference

      HC6.hs is a suppressor of microchaeta phenotype of Su(H)hs.PS

      (Morel et al., 2001)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      HC6.hs partially rescues HP41

      (Maier et al., 1997)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Carried in plasmid "C6" and expressed in S2 cell culture to test for proper protein expression.

      (Maier et al., 1997)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      HC6.hs
      Name Synonyms
      Secondary FlyBase IDs
        References (2)