FlyBase Allele Report: Ecol\lacZ[sli-05248]

General Information

Symbol

Ecol\lacZ^sli-05248

Species

E. coli

Name

FlyBase ID

FBal0085538

Feature type

allele

Associated gene

Ecol\lacZ

Associated Insertion(s)

P{PZ}sli⁰⁵²⁴⁸

Carried in Construct

Also Known As

slit-lacZ

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(BDGP Project Members, 1994-1999)

Progenitor genotype

Associated Insertion(s)

P{PZ}sli⁰⁵²⁴⁸

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{PZ}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:15,922,111..15,922,111 [+]

(Anllo and DiNardo, 2022, Plazaola-Sasieta et al., 2019, Weyers et al., 2011, Fabre et al., 2010, Tayler et al., 2004, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

adult medulla neuropil associated glial cell

(Tayler et al., 2004)

medulla anlage

(Tayler et al., 2004)

adult stage

region of integument | restricted | ventral

(Fabre et al., 2010)

region of integument | dorsal | restricted of adult abdominal segment posterior compartment

(Fabre et al., 2010)

Additional Information

Statement

Reference

Dorsally, sli reporter expression is observed in most of the abdominal segment posterior compartments. Expression is stronger laterally and towards the posterior boundary of the compartment. Ventrally, sli reporter expression is observed in non-sternite regions of integument in lines following the anterior-posterior axis. Expression extends across the midline in regions approximately coextensive with the abdominal segment posterior compartments on the dorsal side.

(Fabre et al., 2010)

EcollacZ^sli-05248 is expressed in medulla glia and cells of the medulla cortex in the developing larval optic lobe.

(Tayler et al., 2004)

Marker for

Reflects expression of

sli

(Tayler et al., 2004)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

12189

P{PZ}sli⁰⁵²⁴⁸ cn¹/CyO; ry⁵⁰⁶

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Ecol\lacZ⁰⁵²⁴⁸

Ecol\lacZ^sli-05248

Slit⁰⁵⁴²⁸

(Plazaola-Sasieta et al., 2019)

lacZ⁰⁵²⁴⁸

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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