FB2024_03 , released June 25, 2024
Allele: Dmel\numbF195V.UAS.Tag:MYC
Open Close
General Information
Symbol
Dmel\numbF195V.UAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0088746
Feature type
allele
Associated gene
Dmel\numb
Associated Insertion(s)
Carried in Construct
P{UAS-numb.T:Myc.F195V}
Key Links
Transgenic product class
missense_variant
(Yaich et al., 1998)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Yaich et al., 1998)
Mutagen
in vitro construct
(Yaich et al., 1998)
Progenitor genotype
numbfl.UAS.Tag:MYC
(Yaich et al., 1998)
Carried in construct
P{UAS-numb.T:Myc.F195V}
Cytology
Description

Construct: Amino acid replacement: F195V.

(Yaich et al., 1998)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
numb
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of numbF195V.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4sca-537.4 has no effect on cell fate specification in the SOP lineage.

      (Tang et al., 2005)

      Flies expressing numbF195V.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4unspecified appear almost indistinguishable from wild-type. Flies expressing numbF195V.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4T80, Scer\GAL41445 or Scer\GAL430A show a very low number of duplicated and/or missing bristles. Embryos expressing numbS148A.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4da.G32 are essentially wild-type. Embryos expressing numbS148A.Scer\UAS.T:Hsap\MYC under the control of both Scer\GAL4twi.PG and Scer\GAL4how-24B have an essentially wild-type pattern of eve-expressing pericardial and dorsal muscle cells.

      (Yaich et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      numbF195V.Scer\UAS.T:Hsap\MYC
      numbF195V.UAS.T:Myc
      numbF195V.UAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (2)