FlyBase Allele Report: Dmel\esg[EP683]

General Information

Symbol

Dmel\esg^EP683

Species

D. melanogaster

Name

FlyBase ID

FBal0089286

Feature type

allele

Associated gene

Dmel\esg

Associated Insertion(s)

P{EP}esg^EP683

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Rorth et al., 1998)

Progenitor genotype

Associated Insertion(s)

P{EP}esg^EP683

Cytology

Description

P{EP} insertion at +692bp of the transcription unit. The P{EP} element is in antisense orientation relative to the transcription unit.

(Abdelilah-Seyfried et al., 2000)

The P{EP} construct is inserted so that an antisense esg transcript is produced.

(Rorth et al., 1998)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:15,333,780..15,333,780 [-]

(Hekmat-Scafe et al., 2005, Singh et al., 2005, Pena-Rangel et al., 2002, Gene Disruption Project members, 2001-, Abdelilah-Seyfried et al., 2000, Ashburner et al., 1999, Ashburner et al., 1999.10.12, Rorth et al., 1998)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^ap-md544

(Pena-Rangel et al., 2002)

Phenotype Manifest In

adult thorax, with Scer\GAL4^ap-md544

(Pena-Rangel et al., 2002)

chaeta, with Scer\GAL4^ap-md544

(Pena-Rangel et al., 2002)

Detailed Description

Statement

Reference

Flies expressing esg^EP683 under the control of Scer\GAL4^ap-md544 have a slight thoracic cleft and loss of chaetae in the dorsal midline.

(Pena-Rangel et al., 2002)

No obvious phenotype.

(Ashburner et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

esg^EP683/Scer\GAL4^pnr-MD237 is an enhancer of visible phenotype of pnr^MD237

(Pena-Rangel et al., 2002)

Suppressor of

Statement

Reference

esg^EP683/Scer\GAL4^ey.PH is a suppressor of visible | dominant phenotype of L²

(Singh et al., 2005)

NOT Suppressor of

Statement

Reference

esg^EP683/Scer\GAL4^elav.PLu is a non-suppressor of bang sensitive phenotype of jus^iso7.8

(Hekmat-Scafe et al., 2005)

Phenotype Manifest In

Enhancer of

Statement

Reference

esg^EP683/Scer\GAL4^pnr-MD237 is an enhancer of adult thorax phenotype of pnr^MD237

(Pena-Rangel et al., 2002)

NOT Enhancer of

Statement

Reference

esg^EP683/Scer\GAL4^sca-537.4 is a non-enhancer of phenotype of N^55e11

(Abdelilah-Seyfried et al., 2000)

Suppressor of

Statement

Reference

esg^EP683/Scer\GAL4^ey.PH is a suppressor of eye | ventral phenotype of L²

(Singh et al., 2005)

Other

Statement

Reference

Scer\GAL4^pnr-MD237, esg^EP683, pnr^MD237/pnr[+] has adult abdomen phenotype

(Pena-Rangel et al., 2002)

Scer\GAL4^pnr-MD237, esg^EP683, pnr^MD237 has adult abdomen phenotype

(Pena-Rangel et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

pnr^MD237/+ adults expressing esg^EP683 under the control of Scer\GAL4^pnr-MD237 have a strong thoracic cleft and defects in the abdominal dorsal midline.

(Pena-Rangel et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: a P{EP} insertion line that modifies the pnr^MD237/+ phenotype when expressed using Scer\GAL4^pnr-MD237.

(Pena-Rangel et al., 2002)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

EP(2)0683

(Abdelilah-Seyfried et al., 2000, Ashburner et al., 1999.10.12)

esg^EP683

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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