FB2024_03 , released June 25, 2024
Allele: Dmel\wgDE
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General Information
Symbol
Dmel\wgDE
Species
D. melanogaster
Name
FlyBase ID
FBal0092444
Feature type
allele
Associated gene
Dmel\wg
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
    Nature of the Allele
    Allele class

    hypomorphic allele - genetic evidence

    (Cavallo et al., 1998)
    Mutagen
    Progenitor genotype
    Caused by aberration
    Df(2L)DE
    Cytology
    Description

    Part of wg regulatory region is removed.

    (Cavallo et al., 1998)

    Part of the wg promoter is removed but the coding region is intact.

    (Dierick and Bejsovec, 1998)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Some but not all pattern elements are evident in the embryonic cuticle.

        (Cavallo et al., 1998)

        wgDE/wgl-17 embryos show all 6 denticle types, separated by small expanses of naked cuticle. These embryos show segmentally repeating dorsal cuticle structures, with a slightly abnormal arrangement.

        (Dierick and Bejsovec, 1998)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Enhanced by
        Statement
        Reference

        wgDE has embryonic epidermis phenotype, enhanceable by panΔN.UAS/Scer\GAL4e22c

        (Cavallo et al., 1998)

        wgDE has ventral denticle belt phenotype, enhanceable by panΔN.UAS/Scer\GAL4e22c

        (Cavallo et al., 1998)
        NOT suppressed by
        Statement
        Reference

        wgPE4/wgDE has embryo | segment polarity expression pattern phenotype, non-suppressible by Df(3L)H99

        (Cox et al., 2000)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Heterozygosity or homozygosity for Df(3L)H99 does not result in noticeable suppression of the wgPE4/wgDE segment polarity phenotype, and there is no noticeable increase in denticle number.

        (Cox et al., 2000)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        wgDE18
        wgDE
        Name Synonyms
        Secondary FlyBase IDs
          References (5)