FlyBase Allele Report: Dmel\Bx[MS1096]

General Information

Symbol

Dmel\Bx^MS1096

Species

D. melanogaster

Name

FlyBase ID

FBal0093489

Feature type

allele

Associated gene

Dmel\Bx

Associated Insertion(s)

P{GawB}Bx^MS1096

Carried in Construct

Also Known As

MS1096-Gal4, MS1096, bx-Gal4, MS1096 Gal4, bx^MS1096-Gal4, MS1096Gal4, MS1096.Gal4, 1096-Gal4, Beadex-Gal4, hdp^MS1096

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Brentrup et al., 2000, Milan and Cohen, 2000, Milan et al., 1998)

Progenitor genotype

Associated Insertion(s)

P{GawB}Bx^MS1096

Cytology

Description

Insertion of a P{GawB} element into the second intron.

(Milan et al., 1998)

Allele components

Component

Use(s)

Inserted element

P{GawB}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible

(Milan et al., 1998)

visible (with Bx^D110)

(Biryukova et al., 2009)

visible (with Bx^D124)

(Biryukova et al., 2009)

visible (with Bx^D128)

(Biryukova et al., 2009)

Phenotype Manifest In

anterior crossvein

(Brentrup et al., 2000)

wing (with Bx^D110)

(Biryukova et al., 2009)

wing (with Bx^D124)

(Biryukova et al., 2009)

wing (with Bx^D128)

(Biryukova et al., 2009)

wing vein

(Milan et al., 1998)

Detailed Description

Statement

Reference

The wing defects caused by Bx^D124 or by Bx^D128 are partially suppressed if the flies also carry Bx^MS1096.

(Biryukova et al., 2009)

Anterior cross vein is absent.

(Brentrup et al., 2000)

Flies have wing venation defects.

(Milan et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Bx^MS1096 has visible phenotype, enhanceable by osa[+]/osa^EP3-941

(Milan et al., 2004)

Suppressed by

Statement

Reference

Bx^MS1096/Bx^D128 has visible phenotype, suppressible by mir-9a^UAS.cBa/Scer\GAL4^Bx-MS1096

(Biryukova et al., 2009)

Bx^MS1096/Bx^D124 has visible phenotype, suppressible | partially by mir-9a^UAS.cBa/Scer\GAL4^Bx-MS1096

(Biryukova et al., 2009)

NOT suppressed by

Statement

Reference

Bx^MS1096/Bx^D110 has visible phenotype, non-suppressible by mir-9a^UAS.cBa/Scer\GAL4^Bx-MS1096

(Biryukova et al., 2009)

Enhancer of

Statement

Reference

Bx^MS1096 is an enhancer of visible | dominant phenotype of Delta^6B

(Milan and Cohen, 2000)

Phenotype Manifest In

Enhanced by

Statement

Reference

Bx^MS1096 has wing phenotype, enhanceable by osa[+]/osa^EP3-941

(Milan et al., 2004)

Suppressed by

Statement

Reference

Bx^MS1096/Bx^D128 has wing phenotype, suppressible by mir-9a^UAS.cBa/Scer\GAL4^Bx-MS1096

(Biryukova et al., 2009)

Bx^MS1096/Bx^D124 has wing phenotype, suppressible | partially by mir-9a^UAS.cBa/Scer\GAL4^Bx-MS1096

(Biryukova et al., 2009)

NOT suppressed by

Statement

Reference

Bx^MS1096/Bx^D110 has wing phenotype, non-suppressible by mir-9a^UAS.cBa/Scer\GAL4^Bx-MS1096

(Biryukova et al., 2009)

Enhancer of

Statement

Reference

Bx^MS1096 is an enhancer of wing vein | ectopic phenotype of Delta^6B

(Milan and Cohen, 2000)

Bx^MS1096 is an enhancer of wing phenotype of Delta^6B

(Milan and Cohen, 2000)

Additional Comments

Genetic Interactions

Statement

Reference

The wing defects seen in Bx^D128/Bx^MS1096 flies are completely suppressed by expression of mir-9a^Scer\UAS.cBa under the control of Scer\GAL4^Bx-MS1096.

The wing defects seen in Bx^D124/Bx^MS1096 flies are partially suppressed by expression of mir-9a^Scer\UAS.cBa under the control of Scer\GAL4^Bx-MS1096.

The wing defects seen in Bx^D110/Bx^MS1096 flies are not affected by expression of mir-9a^Scer\UAS.cBa under the control of Scer\GAL4^Bx-MS1096.

(Biryukova et al., 2009)

The weak wing phenotype of Bx^MS1096/Y flies is slightly enhanced by osa^EP3-941/+.

(Milan et al., 2004)

The ectopic wing vein phenotype of Dl^6B/+ flies is enhanced by Bx^MS1096.

(Milan and Cohen, 2000)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)