FB2024_03 , released June 25, 2024
Allele: Dmel\sca::HsapFGBC286A.UAS
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General Information
Symbol
Dmel\sca::Hsap\FGBC286A.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0093795
Feature type
allele
Associated gene
sca::Hsap\FGB
Associated Insertion(s)
Carried in Construct
P{UAS-sca::Hsap\FGB.C286A}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Lee et al., 1998)
Progenitor genotype
Carried in construct
P{UAS-sca::Hsap\FGB.C286A}
Cytology
Description

A chimeric construct in which amino acids 513 to 774 of sca have been replaced with homologous sequences from Hsap\FGB, with the amino acid replacement: C286A in the Hsap\FGB sequences, is expressed under the control of UAS regulatory sequences.

(Lee et al., 1998)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
sca::Hsap\FGB
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing sca::Hsap\FGBC286A.Scer\UAS under the control of Scer\GAL4dpp.blk1 have nicked wings. Flies expressing sca::Hsap\FGBC286A.Scer\UAS under the control of Scer\GAL4h-1J3 show expansion of wing veins into a "delta" shape.

      (Lee et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Scer\GAL4sca-73-1/sca::Hsap\FGBC286A.UAS is a suppressor of adult thorax & macrochaeta phenotype of sca73-1

      (Lee et al., 1998)

      Scer\GAL4sca-73-1/sca::Hsap\FGBC286A.UAS is a suppressor of adult thorax & macrochaeta phenotype of scaBP2

      (Lee et al., 1998)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      sca::Hsap\FGBC286A.Scer\UAS expressed under the control of Scer\GAL4sca-73-1 partially rescues the scaBP2/sca73-1 extra thoracic bristle phenotype.

      (Lee et al., 1998)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      sca::Hsap\FGBC286A.Scer\UAS
      sca::Hsap\FGBC286A.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)