FB2024_03 , released June 25, 2024
Allele: Dmel\inschs.PKb
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General Information
Symbol
Dmel\inschs.PKb
Species
D. melanogaster
Name
heat shock construct of Knoblich
FlyBase ID
FBal0096873
Feature type
allele
Associated gene
Dmel\insc
Associated Insertion(s)
Carried in Construct
P{hs-insc.Kb}
Also Known As
hs-insc
Key Links
Transgenic product class
wild_type
(Knoblich et al., 1999)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Knoblich et al., 1999)
Mutagen
in vitro construct
(Knoblich et al., 1999, Knoblich et al., 1999)
Progenitor genotype
Carried in construct
P{hs-insc.Kb}
Cytology
Description

Full length insc is expressed under the control of an Hsp70 promoter.

(Knoblich et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
insc
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      inschs.PKb is a suppressor of embryonic neuroblast & spindle phenotype of egl3e/egl1

      (Hughes et al., 2004)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of inschs.PKb rescues the average length of metaphase spindles in neuroblasts of embryos derived from egl3e/egl1 females to a value similar to wild type.

      (Hughes et al., 2004)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      inschs.PKb
      Name Synonyms
      heat shock construct of Knoblich
      (Knoblich et al., 1999, Knoblich et al., 1999)
      Secondary FlyBase IDs
        References (4)