FB2024_03 , released June 25, 2024
Allele: Dmel\armUAS.Tag:MYC,Tag:TM(xNcad)
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General Information
Symbol
Dmel\armUAS.Tag:MYC,Tag:TM(xNcad)
Species
D. melanogaster
Name
FlyBase ID
FBal0097063
Feature type
allele
Associated gene
Dmel\arm
Associated Insertion(s)
Carried in Construct
P{UAS-arm.TM}
Also Known As
Arm-TM
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Cox et al., 1999)
Progenitor genotype
Carried in construct
P{UAS-arm.TM}
Cytology
Description

UASt regulatory sequences drive expression of arm tagged at the N-terminus with a transmembrane domain (Tag:TM(xNcad)) and tagged at the C-terminus with 5 copies of Tag:MYC.

(Cox et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
arm
Tagged with
Tag:MYC
Tag:TM(xNcad)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Embryos expressing armScer\UAS.T:Hsap\MYC,T:Xlae\Ncad under the control of Scer\GAL4e22c die with failure of head involution and occasionally fail to retract the germband.

      (Cox et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      Scer\GAL4e22c/armUAS.Tag:MYC,Tag:TM(xNcad) fails to rescue arm2

      (Cox et al., 1999)

      Scer\GAL4e22c/armUAS.Tag:MYC,Tag:TM(xNcad) fails to rescue arm2

      (Cox et al., 1999)
      Comments

      Expression of armScer\UAS.T:Hsap\MYC,T:Xlae\Ncad under the control of Scer\GAL4e22c has little effect on the wg signaling defects of embryos maternally and zygotically mutant for arm2.

      (Cox et al., 1999)

      Shows little rescue of the segment polarity phenotype of embryos that are maternally and zygotically mutant for arm2, when expressed under the control of Scer\GAL4e22c.

      (Cox et al., 1999)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      armScer\UAS.T:Hsap\MYC,T:Xlae\Ncad
      armUAS.Tag:MYC,Tag:TM(xNcad)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)