FB2024_03 , released June 25, 2024
Allele: Dmel\bab1UAS.cGa
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General Information
Symbol
Dmel\bab1UAS.cGa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Godt
FlyBase ID
FBal0120547
Feature type
allele
Associated gene
Dmel\bab1
Associated Insertion(s)
Carried in Construct
P{UAS-bab1.G}
Also Known As
UAS-bab1
Key Links
Transgenic product class
wild_type
(Couderc et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Couderc et al., 2002)
Mutagen
in vitro construct
(Couderc et al., 2002, Kopp et al., 2000)
Progenitor genotype
Carried in construct
P{UAS-bab1.G}
Cytology
Description

UASt regulatory sequences drive expression of a bab1 minigene, which consists of a 2.7kb PstI-SalI genomic fragment (starting 6bp upstream of the ATG codon and ending 422bp after the 5' splice site of intron 1) and a 4.5kb BamHI genomic fragment (starting 146bp upstream of the 3' splice site of exon 1 and ending 273bp after the end of the bab1 cDNA).

(Couderc et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
bab1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of bab1Scer\UAS.cGa under the control of Scer\GAL4hs.PB results in unpigmented flaccid and wavy macrochaetae on the thorax. Incomplete dorsal closure of the tergites is seen.

      (Bardot et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of bab1Scer\UAS.cGa under the control of Scer\GAL4bab1-Pgal4-2 partially rescues the mutant leg phenotypes of bab2E4/Df(3L)babAr07 flies; there is no sex comb on tarsal segment 3, tarsal segments 4 and 5 are separated by a well-defined joint but there is a small sex comb on tarsal segment 2 (1-2 bristles). bab2E4/Df(3L)babAr07 females have ovaries of reduced size which contain only a few follicles with abnormal orientation. They are subfertile and lay very few eggs. These defects are partially rescued by bab1Scer\UAS.cGa expressed under the control of Scer\GAL4bab1-Pgal4-2.

      (Bardot et al., 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      D. Godt

      (Kopp et al., 2000)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      bab1Scer\UAS.cGa
      bab1UAS.cGa
      babScer\UAS.cGa
      (Kopp et al., 2000)
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Godt
      (Kopp et al., 2000)
      Secondary FlyBase IDs
        References (3)