FlyBase Allele Report: Dmel\egl[EP938]

General Information

Symbol

Dmel\egl^EP938

Species

D. melanogaster

Name

FlyBase ID

FBal0122989

Feature type

allele

Associated gene

Dmel\egl

Associated Insertion(s)

P{EP}egl^EP938

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Kraut et al., 2001, Kraut et al., 2001)

Progenitor genotype

Associated Insertion(s)

P{EP}egl^EP938

Cytology

Description

The P{EP} element is inserted 18 nucleotides 5' to the cDNA start.

(Kraut et al., 2001)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:23,746,839..23,746,839 [-]

(Maybeck and Röper, 2009, Gene Disruption Project members, 2001-, Kraut et al., 2001, Kraut et al., 2001)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with Scer\GAL4^elav-C155

(Kraut et al., 2001)

abnormal neuroanatomy | larval stage, with Scer\GAL4^elav-C155

(Kraut et al., 2001)

Phenotype Manifest In

anterior fascicle & synapse, with Scer\GAL4^elav-C155

(Kraut et al., 2001)

embryonic/larval salivary gland, with Scer\GAL4^fkh.PH

(Maybeck and Röper, 2009)

Detailed Description

Statement

Reference

Expression via Scer\GAL4^fkh.PH produces a strongly penetrant but variable phenotype in the embryonic salivary gland. Glands are C-shaped or shortened.

(Maybeck and Röper, 2009)

Mutant larvae expressing egl^EP938 under the control of Scer\GAL4^elav-C155 have reduced or abnormal synapses.

(Kraut et al., 2001)

In the dorsal muscle region of mutant larvae expressing egl^EP938 under the control of Scer\GAL4^elav-C155, leads to a phenotype in type II synaptic branches. They extend from the ISN and cover a much larger area than normally seen.

(Kraut et al., 2001)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

egl^EP938, Scer\GAL4^GMR.PF is a non-enhancer of abnormal neuroanatomy phenotype of Hsap\ATXN8OS^CTG112.UAS, Scer\GAL4^GMR.PF

(Mutsuddi et al., 2004)

NOT Suppressor of

Statement

Reference

egl^EP938, Scer\GAL4^GMR.PF is a non-suppressor of abnormal neuroanatomy phenotype of Hsap\ATXN8OS^CTG112.UAS, Scer\GAL4^GMR.PF

(Mutsuddi et al., 2004)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

17205

w¹¹¹⁸; P{EP}egl^EP938/CyO

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

egl^EP0938

(Mutsuddi et al., 2004)

egl^EP938

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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