FlyBase Allele Report: Dmel\orb2[BG02373]

General Information

Symbol

Dmel\orb2^BG02373

Species

D. melanogaster

Name

FlyBase ID

FBal0128253

Feature type

allele

Associated gene

Dmel\orb2

Associated Insertion(s)

P{GT1}orb2^BG02373

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Gene Disruption Project members, 2001-)

Progenitor genotype

Associated Insertion(s)

P{GT1}orb2^BG02373

Cytology

Description

The P{GT1}orb2^BG02373 insertion maps within both orb2 and CG43783 (the genes share some exons at the 5' end, including some coding sequence).

(FlyBase, 1996-)

Allele components

Component

Use(s)

Inserted element

P{GT1}

gene trap

polyA trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:8,953,256..8,953,256 [-]

(Gene Disruption Project members, 2001-, FlyBase, 1996-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal starvation stress response | dominant

(Zhang et al., 2010)

long lived | dominant

(Zhang et al., 2010)

Phenotype Manifest In

Detailed Description

Statement

Reference

The rough eye phenotype observed in Fmr1^sev.PW flies is suppressed in a orb2^BG02373/+ background.

(Cziko et al., 2009)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

orb2^BG02373 has abnormal starvation stress response | dominant phenotype, non-enhanceable by hyx^EY06898

(Zhang et al., 2010)

Suppressed by

Statement

Reference

orb2^BG02373 has abnormal starvation stress response | dominant phenotype, suppressible by Scer\GAL4^Act5C.PU/hyx^EY06898

(Zhang et al., 2010)

NOT suppressed by

Statement

Reference

orb2^BG02373 has abnormal starvation stress response | dominant phenotype, non-suppressible by hyx^EY06898

(Zhang et al., 2010)

Enhancer of

Statement

Reference

orb2[+]/orb2^BG02373 is an enhancer of visible | dominant phenotype of N^55e11

(Kankel et al., 2007)

NOT Enhancer of

Statement

Reference

orb2^BG02373 is a non-enhancer of abnormal starvation stress response | dominant phenotype of hyx^EY06898

(Zhang et al., 2010)

Suppressor of

Statement

Reference

orb2^BG02373 is a suppressor of visible | dominant | adult stage phenotype of L^si

(Zhang et al., 2010)

NOT Suppressor of

Statement

Reference

orb2^BG02373 is a non-suppressor of abnormal starvation stress response | dominant phenotype of hyx^EY06898

(Zhang et al., 2010)

Other

Statement

Reference

L^si, hyx^EY06898, orb2^BG02373 has visible | adult stage phenotype

(Zhang et al., 2010)

L^si, hyx^EY06898, orb2^BG02373 has increased occurrence of cell division | third instar larval stage phenotype

(Zhang et al., 2010)

Phenotype Manifest In

Enhancer of

Statement

Reference

orb2[+]/orb2^BG02373 is an enhancer of wing phenotype of N^55e11

(Kankel et al., 2007)

NOT Enhancer of

Statement

Reference

hyx^EY06898/orb2^BG02373 is a non-enhancer of eye disc | third instar larval stage phenotype of L^si

(Zhang et al., 2010)

Suppressor of

Statement

Reference

orb2^BG02373 is a suppressor of eye | ventral phenotype of L^si

(Zhang et al., 2010)

orb2[+]/orb2^BG02373 is a suppressor of eye phenotype of Fmr1^sev.PW

(Cziko et al., 2009)

NOT Suppressor of

Statement

Reference

hyx^EY06898/orb2^BG02373 is a non-suppressor of eye disc | third instar larval stage phenotype of L^si

(Zhang et al., 2010)

Other

Statement

Reference

L^si, hyx^EY06898, orb2^BG02373 has eye phenotype

(Zhang et al., 2010)

L^si, hyx^EY06898, orb2^BG02373 has interommatidial bristle phenotype

(Zhang et al., 2010)

L^si, hyx^EY06898, orb2^BG02373 has eye disc | third instar larval stage phenotype

(Zhang et al., 2010)

L^si, hyx^EY06898, orb2^BG02373 has ommatidium | adult stage phenotype

(Zhang et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

Dominantly enhances the Df(1)N-54l9/+ and N^55e11/+ wing nicking phenotypes.

(Kankel et al., 2007)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

CG5735^BG02373

orb2^BG02373

(Zhang et al., 2010, Cziko et al., 2009, Kankel et al., 2007)

orb2^BG2373

(Zhang et al., 2010)

orb^BG02373

(Cziko et al., 2009)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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