FlyBase Allele Report: Dmel\ball[EP863]

General Information

Symbol

Dmel\ball^EP863

Species

D. melanogaster

Name

FlyBase ID

FBal0131762

Feature type

allele

Associated gene

Dmel\ball

Associated Insertion(s)

P{EP}ball^EP863

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

loss of function allele

hypomorphic allele - genetic evidence

Mutagen

P-element activity

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Klinge, 2004.2.25)

loss of function allele

(Zhu et al., 2005)

Mutagen

P-element activity

(Gene Disruption Project members, 2001-)

Progenitor genotype

Associated Insertion(s)

P{EP}ball^EP863

Cytology

Description

Insertion in the second exon.

(Zhu et al., 2005)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:26,866,561..26,866,561 [-]

(Park and Song, 2008, Zhu et al., 2005, Zhu et al., 2005, Klinge, 2004.2.25, Gene Disruption Project members, 2001-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female semi-fertile

(Cullen et al., 2005)

lethal | embryonic stage

(Zhu et al., 2005)

lethal | larval stage

(Zhu et al., 2005)

male sterile | recessive

(Klinge, 2004.2.25)

viable

(Cullen et al., 2005)

Phenotype Manifest In

testis

(Klinge, 2004.2.25)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

ball^EP863/Scer\GAL4^GMR.PU is an enhancer of visible phenotype of Scer\GAL4^GMR.PU, lok^UAS.cPb

(Park and Song, 2008)

NOT Enhancer of

Statement

Reference

ball^EP863, Scer\GAL4^GMR.PU is a non-enhancer of visible phenotype of N^UAS.cMa, Scer\GAL4^GMR.PU

(Park and Song, 2008)

ball^EP863, Scer\GAL4^GMR.PF is a non-enhancer of visible phenotype of Rac1^N17.UAS, Scer\GAL4^GMR.PF

(Zhu et al., 2005)

ball^EP863, Scer\GAL4^GMR.PF is a non-enhancer of visible phenotype of Cdc42^L89.UAS, Scer\GAL4^GMR.PF

(Zhu et al., 2005)

Scer\GAL4^GMR.PF/ball^EP863 is a non-enhancer of visible phenotype of Scer\GAL4^GMR.PF, btl::Egfr^λ.UAS

(Zhu et al., 2005)

Suppressor of

Statement

Reference

Scer\GAL4^GMR.PF/ball^EP863 is a suppressor of visible phenotype of Scer\GAL4^GMR.PF, btl^λ.UAS, stumps^UAS.Tag:FLAG

(Zhu et al., 2005)

ball^EP863, Scer\GAL4^GMR.PF is a suppressor of visible phenotype of Pvr^λ.UAS, Scer\GAL4^GMR.PF

(Zhu et al., 2005)

NOT Suppressor of

Statement

Reference

ball^EP863, Scer\GAL4^GMR.PF is a non-suppressor of visible phenotype of Rac1^N17.UAS, Scer\GAL4^GMR.PF

(Zhu et al., 2005)

ball^EP863, Scer\GAL4^GMR.PF is a non-suppressor of visible phenotype of Cdc42^L89.UAS, Scer\GAL4^GMR.PF

(Zhu et al., 2005)

Scer\GAL4^GMR.PF/ball^EP863 is a non-suppressor of visible phenotype of Scer\GAL4^GMR.PF, btl::Egfr^λ.UAS

(Zhu et al., 2005)

Phenotype Manifest In

Enhancer of

Statement

Reference

ball^EP863/Scer\GAL4^GMR.PU is an enhancer of eye phenotype of Scer\GAL4^GMR.PU, lok^UAS.cPb

(Park and Song, 2008)

NOT Enhancer of

Statement

Reference

ball^EP863, Scer\GAL4^GMR.PU is a non-enhancer of eye phenotype of N^UAS.cMa, Scer\GAL4^GMR.PU

(Park and Song, 2008)

Scer\GAL4^GMR.PF/ball^EP863 is a non-enhancer of eye phenotype of Scer\GAL4^GMR.PF, btl::Egfr^λ.UAS

(Zhu et al., 2005)

ball^EP863 is a non-enhancer of embryonic/larval dorsal tracheal branch phenotype of stumps^ems7

(Zhu et al., 2005)

Suppressor of

Statement

Reference

Scer\GAL4^GMR.PF/ball^EP863 is a suppressor of eye phenotype of Scer\GAL4^GMR.PF, btl^λ.UAS, stumps^UAS.Tag:FLAG

(Zhu et al., 2005)

ball^EP863, Scer\GAL4^GMR.PF is a suppressor of eye phenotype of Pvr^λ.UAS, Scer\GAL4^GMR.PF

(Zhu et al., 2005)

NOT Suppressor of

Statement

Reference

Scer\GAL4^GMR.PF/ball^EP863 is a non-suppressor of eye phenotype of Scer\GAL4^GMR.PF, btl::Egfr^λ.UAS

(Zhu et al., 2005)

ball^EP863 is a non-suppressor of embryonic/larval dorsal tracheal branch phenotype of stumps^ems7

(Zhu et al., 2005)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of ball^EP863 enhances the rough eye phenotype seen when lok^Scer\UAS.cPb is expressed under the control of Scer\GAL4^GMR.PU.

Expression of ball^EP863 does not enhance the rough eye phenotype seen when N^Scer\UAS.cMa is expressed under the control of Scer\GAL4^GMR.PU.

(Park and Song, 2008)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

ball^trip

(Cullen et al., 2005)

Comments

The poor fertility seen in ball^EP863 mutants is not complemented by ball^trip.

(Cullen et al., 2005)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Precise excision of the P{EP} element indicates that the lethality of the chromosome is associated with the insertion.

(Zhu et al., 2005)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

BcDNA:LD09009^EP863

CG6386^EP0863

(Zhu et al., 2005)

CG6386^EP863

ball^EP863

ballchen^EP863

nhk-1^EP

(Cullen et al., 2005)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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