FlyBase Allele Report: Dmel\bab1[PR72]

General Information

Symbol

Dmel\bab1^PR72

Species

D. melanogaster

Name

FlyBase ID

FBal0138347

Feature type

allele

Associated gene

Dmel\bab1

Associated Insertion(s)

Carried in Construct

Also Known As

bab^PR72

Key Links

Allele class

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

Mutagen

Delta2-3 transposase

(Godt et al., 1993)

Progenitor genotype

bab1^P

(Godt et al., 1993)

Caused by aberration

Df(3L)bab^PR72

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Df(3L)Fpa2, bab1^PR72, bab2^PR72 has visible phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab1^PR72, bab2^PR72 has abnormal body color phenotype

(Couderc et al., 2002)

bab1^PR72, bab2^PR72 has visible | recessive phenotype

(Couderc et al., 2002, Godt et al., 1993)

bab1^PR72, bab2^PR72 has female sterile | recessive phenotype

(Couderc et al., 2002, Godt et al., 1993)

bab1^PR72, bab2^PR72 has visible | dominant | heat sensitive phenotype

(Godt et al., 1993)

Phenotype Manifest In

Other

Statement

Reference

bab1^PR72, bab2^PR72 has tarsal segment 4 phenotype

(Couderc et al., 2002)

bab1^PR72, bab2^PR72 has ovariole phenotype

(Couderc et al., 2002)

bab1^PR72, bab2^PR72 has metathoracic tarsal bristle transverse row | ectopic phenotype

(Couderc et al., 2002)

bab1^PR72, bab2^PR72 has pretarsus phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab1^PR72, bab2^PR72 has abdominal sternite 6 | female phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab1^PR72, bab2^PR72 has abdominal sternite 7 | female phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab1^PR72, bab2^PR72 has abdominal tergite 2 | anterior phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab1^PR72, bab2^PR72 has abdominal tergite 3 | anterior phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab1^PR72, bab2^PR72 has abdominal tergite 4 | anterior phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab1^PR72, bab2^PR72 has abdominal tergite 5 | anterior phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab1^PR72, bab2^PR72 has abdominal tergite 6 | anterior phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab1^PR72, bab2^PR72 has abdominal tergite 7 | anterior phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab1^PR72, bab2^PR72 has abdominal tergite 8 | anterior phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab1^PR72, bab2^PR72 has chaeta & abdominal sternite 6 | female phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab1^PR72, bab2^PR72 has chaeta & abdominal sternite 7 | female phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab1^PR72, bab2^PR72 has hypogynial tooth phenotype

(Couderc et al., 2002)

bab1^PR72, bab2^PR72 has sex comb | ectopic phenotype

(Couderc et al., 2002, Godt et al., 1993)

bab1^PR72, bab2^PR72 has prothoracic tarsal segment 2 phenotype

(Couderc et al., 2002, Godt et al., 1993)

bab1^PR72, bab2^PR72 has prothoracic tarsal segment 3 phenotype

(Couderc et al., 2002, Godt et al., 1993)

bab1^PR72, bab2^PR72 has metathoracic tarsal segment 3 phenotype

(Couderc et al., 2002, Godt et al., 1993)

bab1^PR72, bab2^PR72 has leg phenotype

(Couderc et al., 2002, Godt et al., 1993)

bab1^PR72, bab2^PR72 has ovary phenotype

(Couderc et al., 2002, Godt et al., 1993)

bab1^PR72, bab2^PR72 has terminal filament phenotype

(Godt and Laski, 1995)

bab1^PR72, bab2^PR72 has antenna phenotype

(Godt et al., 1993)

bab1^PR72, bab2^PR72 has basal cylinder phenotype

(Godt et al., 1993)

bab1^PR72, bab2^PR72 has macrochaeta phenotype

(Godt et al., 1993)

bab1^PR72, bab2^PR72 has prothoracic tarsal segment 4 phenotype

(Godt et al., 1993)

bab1^PR72, bab2^PR72 has prothoracic tarsal segment 5 phenotype

(Godt et al., 1993)

bab1^PR72, bab2^PR72 has mesothoracic tarsal segment 2 phenotype

(Godt et al., 1993)

bab1^PR72, bab2^PR72 has mesothoracic tarsal segment 3 phenotype

(Godt et al., 1993)

bab1^PR72, bab2^PR72 has mesothoracic tarsal segment 4 phenotype

(Godt et al., 1993)

bab1^PR72, bab2^PR72 has mesothoracic tarsal segment 5 phenotype

(Godt et al., 1993)

bab1^PR72, bab2^PR72 has metathoracic tarsal segment 2 phenotype

(Godt et al., 1993)

bab1^PR72, bab2^PR72 has metathoracic tarsal segment 4 phenotype

(Godt et al., 1993)

bab1^PR72, bab2^PR72 has metathoracic tarsal segment 5 phenotype

(Godt et al., 1993)

Additional Comments

Genetic Interactions

Statement

Reference

Homozygous Df(3L)bab^PR72 females have a strong mutant ovary phenotype; the ovaries are very small and contain only 1-2 ovarioles of very abnormal structure and orientation and the females do not lay eggs. Df(3L)bab^PR72 homozygotes have a strong mutant leg phenotype; tarsal segments TS1-TS3 of the prothoracic leg have sex comb bristles (normally only found on TS1) and tarsal segments TS1-TS3 of the metathoracic leg have transverse bristle rows (normally only found on TS1 and TS2). Segments TS5 and TS4 are fused. Df(3L)bab^PR72/Df(3L)Fpa2 females show ectopic dark pigmentation in the anterior portion of tergites A3-A8 and also with low penetrance in A2. The ectopic dark pigmentation in A2 and A3 is patchy and usually restricted to the anterior margin. The two rows of thorn bristles are replaced by a different type of bristle, which are longer and twisted in Df(3L)bab^PR72/Df(3L)Fpa2 females. The shape, pigmentation pattern and bristle pattern of the A6 and A7 sternites in Df(3L)bab^PR72/Df(3L)Fpa2 females are different from wild-type females and more show similarities to the A6 sternite in wild-type males.

(Couderc et al., 2002)

Homozygous Df(3L)bab^PR72 females have a severely reduced ovariole number or lack ovarioles altogether due to the disruption of terminal filament formation.

(Godt and Laski, 1995)

Bristle pattern of tarsal segments T2, T3 and T4 is transformed to that of T1 in Df(3L)bab^PR72 mutants. Homozygous Df(3L)bab^PR72 males have ectopic sex combs in tarsal segments 2, 3 and occasionally 4, and fusion of tarsal segments 4 and 5. Additionally the two segments of the antennal basal cylinder are fused. Heterozygous males have an ectopic sex comb on tarsal segment 2.

(Godt et al., 1993)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

bab1^PR72

bab^PR72

(Godt and Laski, 1995, Godt et al., 1993)

Name Synonyms

Secondary FlyBase IDs

FBal0030549

References (3)

Report Sections

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