FB2024_03 , released June 25, 2024
Allele: Dmel\Prx4AKP.Ub.GMR
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General Information
Symbol
Dmel\Prx4AKP.Ub.GMR
Species
D. melanogaster
Name
FlyBase ID
FBal0144784
Feature type
allele
Associated gene
Dmel\Prx4
Associated Insertion(s)
Carried in Construct
P{GMR-Prx4.AKP}
Key Links
Transgenic product class
inframe_deletion
(Tenev et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Tenev et al., 2002)
Mutagen
in vitro construct
(Tenev et al., 2002)
Progenitor genotype
Carried in construct
P{GMR-Prx4.AKP}
Cytology
Description

GMR regulatory sequences drive expression of Jafrac2 missing the N terminal 17 amino acids and fused at the N terminus to a Ubiquitin moeity.

(Tenev et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
GMR
Encoded product / tool
Prx4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Jafrac2AKP.Ub.GMR induces ectopic cell death that causes a 'spotted eye' phenotype, exhibiting occasional red spots, despite being in a w- background.

      (Tenev et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      Prx4AKP.Ub.GMR has increased cell death phenotype, suppressible by Diap1GMR.PH

      (Tenev et al., 2002)

      Prx4AKP.Ub.GMR has increased cell death phenotype, suppressible by Diap14

      (Tenev et al., 2002)

      Prx4AKP.Ub.GMR has increased cell death phenotype, suppressible by BacA\p35GMR.PH

      (Tenev et al., 2002)
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Prx4AKP.Ub.GMR has eye phenotype, suppressible by BacA\p35GMR.PH

      (Tenev et al., 2002)

      Prx4AKP.Ub.GMR has eye phenotype, suppressible by Diap14

      (Tenev et al., 2002)

      Prx4AKP.Ub.GMR has eye phenotype, suppressible by Diap1GMR.PH

      (Tenev et al., 2002)

      Prx4AKP.Ub.GMR has eye phenotype, suppressible | partially by Df(3L)AC1

      (Tenev et al., 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Jafrac2AKP.Ub.GMR
      Prx4AKP.Ub.GMR
      Name Synonyms
      Secondary FlyBase IDs
        References (1)