FlyBase Allele Report: Dmel\Diap1[33-1s]

General Information

Symbol

Dmel\Diap1^33-1s

Species

D. melanogaster

Name

FlyBase ID

FBal0146758

Feature type

allele

Associated gene

Dmel\Diap1

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Premature stop codon after amino acid 350 resulting in a protein which lacks the RING domain.

(Ryoo et al., 2002)

Amino acid replacement: Q336term.

(Wilson et al., 2002)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

3L:16,038,983..16,038,983 [-]

Nucleotide change:

C16038983T

Amino acid change:

Reported amino acid change:

Q336term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Wilson et al., 2002)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Diap1^33-1s is an enhancer of visible phenotype of rpr^GMR.PW

(Wilson et al., 2002)

Diap1^33-1s is an enhancer of visible phenotype of Dronc^pro.UAS, Scer\GAL4^GMR.PF

(Wilson et al., 2002)

Suppressor of

Statement

Reference

Diap1^33-1s/Diap1[+] is a suppressor | partially of decreased size | adult stage phenotype of Scer\GAL4^nub.PU, syd^GLC01419

(Ahmad et al., 2021)

Diap1^33-1s/Diap1[+] is a suppressor | partially of visible | adult stage phenotype of Scer\GAL4^nub.PU, syd^GLC01419

(Ahmad et al., 2021)

Diap1^33-1s is a suppressor of visible phenotype of hid^GMR.PG

(Wilson et al., 2002)

Phenotype Manifest In

Enhancer of

Statement

Reference

Diap1^33-1s is an enhancer of eye phenotype of rpr^GMR.PW

(Wilson et al., 2002)

Diap1^33-1s is an enhancer of eye phenotype of Dronc^pro.UAS, Scer\GAL4^GMR.PF

(Wilson et al., 2002)

Suppressor of

Statement

Reference

Diap1^33-1s is a suppressor of eye phenotype of hid^GMR.PG

(Wilson et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

The small eye phenotype of rpr^GMR.PW flies is significantly enhanced by th^33-1s. The ablated eye phenotype of rpr^GMR.PW flies is suppressed by th^33-1s.

(Wilson et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

Diap1^33-1s

diap1^(33-1s)

(Ahmad et al., 2021)

diap1^33-1S

(Ryoo et al., 2002)

diap1^33-1s

(Shapiro et al., 2008, Ryoo et al., 2004)

diap^33-1s

(Ahmad et al., 2021)

th^33-1s

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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