Expression Sara, tagged with Tag:MYC and Tag:polyHis at the N-terminus, is under the control of UAS sequences.
Posterior midgut clones expressing SaraScer\UAS.T:Hsap\MYC,T:Zzzz\His6 under the control of Scer\GAL4Act5C.PP do not exhibit any defects in cell viability or proliferation rate. A higher proportion of intestinal stem cell (ISC) symmetric divisions occurs compared to wild type.
SaraScer\UAS.T:Hsap\MYC,T:Zzzz\His6; Scer\GAL4vg.int2.1 flies show variable minor loss of posterior wing margin.