FB2024_03 , released June 25, 2024
Allele: Dmel\Mod(Prat:bw)3-53-5
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General Information
Symbol
Dmel\Mod(Prat:bw)3-53-5
Species
D. melanogaster
Name
FlyBase ID
FBal0152393
Feature type
allele
Associated gene
Mod(Prat:bw)3-5
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Malmanche and Clark, 2003)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhancer of
      Statement
      Reference

      Mod(Prat:bw)3-53-5 is a non-enhancer of abnormal eye color phenotype of bw+t8.4, bwD

      (Malmanche and Clark, 2003)
      Suppressor of
      Statement
      Reference

      Mod(Prat:bw)3-53-5/Mod( Prat:bw )3-5[+] is a suppressor of abnormal eye color phenotype of bwD, bwPrat.PC

      (Malmanche and Clark, 2003)
      NOT Suppressor of
      Statement
      Reference

      Mod(Prat:bw)3-53-5 is a non-suppressor of abnormal eye color phenotype of bw+t8.4, bwD

      (Malmanche and Clark, 2003)
      Phenotype Manifest In
      NOT Enhancer of
      Statement
      Reference

      Mod(Prat:bw)3-53-5 is a non-enhancer of pigment cell phenotype of bw+t8.4, bwD

      (Malmanche and Clark, 2003)
      Suppressor of
      Statement
      Reference

      Mod(Prat:bw)3-53-5/Mod( Prat:bw )3-5[+] is a suppressor of pigment cell phenotype of bwD, bwPrat.PC

      (Malmanche and Clark, 2003)
      NOT Suppressor of
      Statement
      Reference

      Mod(Prat:bw)3-53-5 is a non-suppressor of pigment cell phenotype of bw+t8.4, bwD

      (Malmanche and Clark, 2003)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: a mutation that alters the eye colour of bwPrat.PC/bwD flies.

      (Malmanche and Clark, 2003)
      Comments
      Comments

      5 modifier alleles isolated in this screen form a complex complementation group on the third chromosome; a first subgroup consisting of Mod(Prat:bw)3-13-1, Mod(Prat:bw)3-23-2 and Mod(Prat:bw)3-33-3, a second subgroup of Mod(Prat:bw)3-33-3 and Mod(Prat:bw)3-43-4 and a third subgroup of Mod(Prat:bw)3-43-4 and Mod(Prat:bw)3-53-5. It is not clear whether these 5 alleles represent a single gene with some complementing alleles or whether there are second-site mutations associated with some of the modifier chromosomes, although evidence suggests that there are second-site mutations on the Mod(Prat:bw)3-33-3 and Mod(Prat:bw)3-43-4 chromosomes that affect the result obtained for these two alleles.

      (Malmanche and Clark, 2003)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Mod(Prat:bw)3-53-5
      Mod-3-5
      (Malmanche and Clark, 2003)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)