FB2024_03 , released June 25, 2024
Allele: Dmel\Tango5G0145b
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General Information
Symbol
Dmel\Tango5G0145b
Species
D. melanogaster
Name
FlyBase ID
FBal0152706
Feature type
allele
Associated gene
Dmel\Tango5
Associated Insertion(s)
P{lacW}Tango5G0145b
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Peter et al., 2002)
Progenitor genotype
Associated Insertion(s)
P{lacW}Tango5G0145b
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
AJ426846
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  tauopathy
      modeled by Hsap\MAPTGMR.Ex.PJ
      (Ambegaokar and Jackson, 2011)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Tango5[+]/Tango5G0145b is an enhancer of visible phenotype of Hsap\MAPTGMR.Ex.PJ

      (Ambegaokar and Jackson, 2011)
      NOT Suppressor of
      Statement
      Reference

      Tango5[+]/Tango5G0145b is a non-suppressor of visible phenotype of Scer\GAL4GMR.PU, Zzzz\CAGQ108.UAS

      (Ambegaokar and Jackson, 2011)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Tango5[+]/Tango5G0145b is an enhancer of eye phenotype of Hsap\MAPTGMR.Ex.PJ

      (Ambegaokar and Jackson, 2011)
      NOT Suppressor of
      Statement
      Reference

      Tango5[+]/Tango5G0145b is a non-suppressor of eye phenotype of Scer\GAL4GMR.PU, Zzzz\CAGQ108.UAS

      (Ambegaokar and Jackson, 2011)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      One copy of Tango5G0145b mildly enhances the apoptosis seen in flies overexpressing hid.

      (Ambegaokar and Jackson, 2011)
      Xenogenetic Interactions
      Statement
      Reference

      One copy of Tango5G0145b enhances the rough eye phenotype seen in flies expressing Hsap\MAPTGMR.Ex.PJ. Necrotic plaques are also seen.

      One copy of Tango5G0145b does not suppress the rough eye phenotype seen in flies expressing Zzzz\CAGQ108.Scer\UAS under the control of Scer\GAL4GMR.PU.

      (Ambegaokar and Jackson, 2011)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Separable from: P{lacW}G0145a. Separable from: P{lacW}G0145c.

      (Peter et al., 2002)
      External Crossreferences and Linkouts ( 1 )
      Crossreferences
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      CG32675G0145b
      Tango5G0145b
      (Ambegaokar and Jackson, 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)