FB2024_03 , released June 25, 2024
Allele: Lpol\Ops1ninaE.PK
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General Information
Symbol
Lpol\Ops1ninaE.PK
Species
L. polyphemus
Name
neither inactivation nor afterpotential E promoter construct of Knox
FlyBase ID
FBal0156285
Feature type
allele
Associated gene
Lpol\Ops1
Associated Insertion(s)
Carried in Construct
P{ninaE-LimRh1.K}
Transgenic product class
cDNA
(Knox et al., 2003)
wild_type
(Knox et al., 2003)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Knox et al., 2003)
wild_type
(Knox et al., 2003)
Mutagen
in vitro construct
(Knox et al., 2003)
Progenitor genotype
Carried in construct
P{ninaE-LimRh1.K}
Cytology
Description

A ninaE fragment containing 2.5kb of promoter sequence, the transcription start site and 33bp of the 5' untranslated region is fused upstream of a wild-type Lpol\Ops1 cDNA. 650bp of the 3' end of the ninaE gene (including the polyadenylation signal) are also present.

(Knox et al., 2003)
Allele components
Component
Use(s)
Regulatory region(s)
ninaE
Encoded product / tool
Lpol\Ops1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Lpol\Ops1ninaE.PK is a suppressor of rhabdomere phenotype of ninaE17

      (Pinal and Pichaud, 2011)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of Lpol\Ops1ninaE.PK rescues the rhabdomere morphogenesis defects of ninaE17 flies.

      (Pinal and Pichaud, 2011)

      Introduction of Lpol\Ops1ninaE.PK into a norpA36;ninaE17/ninaE17; norpAninaE.PM background restores the response to light (measured using an ERG recording), although the response at 520nm is much great than that at 350nm. Flies expressing Lpol\Ops1ninaE.PK in a ninaE17 Gα49B1 background show no response to light (measured using an ERG recording). Flies expressing Lpol\Ops1ninaE.PK in a ninaE17 norpA36 background show no response to light (measured using an ERG recording).

      (Knox et al., 2003)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Lpol\Ops1ninaE.PK
      Name Synonyms
      neither inactivation nor afterpotential E promoter construct of Knox
      (Knox et al., 2003)
      Secondary FlyBase IDs
        References (2)