FB2024_03 , released June 25, 2024
Allele: Dmel\DIP1EY02625
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General Information
Symbol
Dmel\DIP1EY02625
Species
D. melanogaster
Name
FlyBase ID
FBal0156748
Feature type
allele
Associated gene
Dmel\DIP1
Associated Insertion(s)
P{EPgy2}DIP1EY02625
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{EPgy2}DIP1EY02625
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EPgy2}
Regulatory region(s)
UASp
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The survival rate of DIP1EY02625 mutants after DCV infection is 45% compared to controls. Median survival is ~3.5 days. The amount of DCV RNA increases sharply in the mutants after 24 h following infection, whereas DCV levels remain undetectable by 72 hours after infection in wild type.

      (Zhang et al., 2015)

      DIP1EY02625 flies have a restrictive phenotype with respect to gypsy expression (assayed by expression of a P{gypsy-lacZ.p12} reporter construct in the ovaries).

      DIP1EY02625 flies are stable for ZAM expression (assayed by expression of a P{ZAM-lacZ.LTR} reporter construct in the ovaries).

      (Mevel-Ninio et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      Comments

      DIP1EY02625 is not a flam mutant; it is female fertile, complements the flamBG02658 female sterile phenotype and is restrictive with respect to gypsy expression (assayed by expression of a P{gypsy-lacZ.p12} reporter construct in the ovaries).

      (Mevel-Ninio et al., 2007)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      DIP1EY02625
      (Tay and Pek, 2019, Wong et al., 2017)
      Dip1
      (Nickel et al., 2005)
      dip1EY02625
      (Zhang et al., 2015)
      flamEY(R)
      (Mevel-Ninio et al., 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)