The size of regenerated adult wings in mole02670 heterozygous mutants that were subjected to ablation of the imaginal wing disc tissue during the larval stage, is significantly decreased compared to similarly treated controls. The regeneration appears to proceed more slowly in the mutant larvae as assessed by size of the regenerating wing pouch over time.
Homozygous mole02670 embryos are developmentally arrested soon after hatching and exhibit gross developmental defects, dying at the first instar larval stage.
mole02670 germline clone females produce embryos with an 80% hatch-rate. Although the size of wild-type or mutant embryos are comparable when they hatch, after 24 hours the wild-type larvae are approximately twice as long as the mutant. Mutant larvae hardly grow at all during an extended 1st instar larval period during which time a wild-type larva reaches a body length 4-5 times that of the mutant. Despite the remarkable growth retardation of the mutant embryo, the cuticle of the 1st instar larvae (L1) shows no major defect in comparison to wild-type controls. However, the tracheal system of the mutant embryo appears underdeveloped. Mallory staining reveals gross defects in the development of inner organs, with mole02670 mutant larvae showing no distinctive features in the gut and annexes, suggesting gross developmental defects. These defects manifest in the feeding pattern of the mutant larvae such that they are lethargic in feeding and have a lower food intake than wild-type larvae.
mole02670 has visible | adult stage phenotype, suppressible by pucE69/puc[+]
mole02670 has abnormal stress response | adult stage phenotype, suppressible by pucE69/puc[+]
mole02670 is rescued by molUAS.cXa/Scer\GAL4αTub84B.PL
mole02670 is rescued by Scer\GAL4Act5C.PI/molUAS.cXa
mole02670 is rescued by molUAS.cXa/Scer\GAL4hs.PB
mole02670 is rescued by molN1N2.UAS/Scer\GAL4αTub84B.PL
mole02670 is rescued by Scer\GAL4Act5C.PI/molN1N2.UAS
mole02670 is rescued by molN1N2.UAS/Scer\GAL4hs.PB