FB2024_03 , released June 25, 2024
Allele: Dmel\vvlRNAi.UAS
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General Information
Symbol
Dmel\vvlRNAi.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0177190
Feature type
allele
Associated gene
Dmel\vvl
Associated Insertion(s)
Carried in Construct
P{UAS-vvl.RNAi}
Also Known As
UAS-dsdfr
Key Links
Transgenic product class
RNAi_reagent
(Certel and Thor, 2004)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Certel and Thor, 2004)
Mutagen
in vitro construct
(Certel and Thor, 2004)
Progenitor genotype
Carried in construct
P{UAS-vvl.RNAi}
Cytology
Description

UASt sequences drive expression of an inverted 791 bp repeat of vvl coding sequence (corresponds to nucleotides 517-1308).

(Certel and Thor, 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
vvl
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expressing vvldsRNA.UAS under the control of Scer\GAL4da.G32 in a vvldfr-B129 heterozygous background results in melanized spots in the cuticle, Malpighian tubules and gastric caecum, and abnormal morphology of the fat body in third instar larvae. Expressing vvldsRNA.UAS under the control of Scer\GAL4c729 in a vvldfr-B129 heterozygous background results in melanized tissues and death prior to eclosion.

      (Junell et al., 2010)

      In vvldsRNA.Scer\UAS, vvldfr-B129/+ embryos with Scer\GAL4Lim3.B or Scer\GAL4ftz.ng, ISNb motor axons leave the ventral muscle field and contact or target the transverse nerve (TN) fascicle. There is also an overall decrease in muscle innervation by ISNb motor axons in these embryos.

      (Certel and Thor, 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      vvlRNAi.UAS
      vvldsRNA.Scer\UAS
      vvldsRNA.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (4)