FB2024_03 , released June 25, 2024
Allele: Dmel\chn19E
Open Close
General Information
Symbol
Dmel\chn19E
Species
D. melanogaster
Name
FlyBase ID
FBal0193097
Feature type
allele
Associated gene
Dmel\chn
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Reeves and Posakony, 2005)
Progenitor genotype
P{SUPor-P}KG03781
(Reeves and Posakony, 2005)
Caused by aberration
Df(2R)chn19E
Cytology
Description

Imprecise excision of P{SUPor-P}KG03781 has deleted sequence extending from the P{SUPor-P}KG03781 insertion site into the final exon of chn including all of the 3' UTR.

(Reeves and Posakony, 2005)

FlyBase curator comment: Figure 5 of FBrf0183881 indicates that the deletion in the chn19E allele extends upstream from the site of the progenitor insertion (P{SUPor-P}KG03781) through to a location within the chn locus. This means that the deletion must also remove the Polr2K gene, as this gene lies in the region between the end of the chn transcription unit and the location of the P{SUPor-P}KG03781 insertion.

(FlyBase, 1996-)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The peripheral nervous system of chn19E homozygous embryos has structural defects.

      (Reeves and Posakony, 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      chn19E
      (Reeves and Posakony, 2005)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)