FB2024_03 , released June 25, 2024
Allele: Dmel\gcm2UAS.cCa
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General Information
Symbol
Dmel\gcm2UAS.cCa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Chotard
FlyBase ID
FBal0194172
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UASt regulatory sequences drive expression of a 2.5kb gcm2 fragment.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of gcm2Scer\UAS.cCa under the control of Scer\GAL4lama-A8 results in unhealthy larvae. However, these larvae produce no additional glial cells at the expense of neurons within the lamina at the level of the R-cell projection filed or glial precursor cell areas.

Induction of clones in the eye disc which express gcm2Scer\UAS.cCa under the control of Scer\GAL4Act5C.PI leads to disruption of the formation of R-cells in the eye and, thus, with optic lobe development. Although no excess glial cells are seen in the eye, these clones do induce ectopic glial cells within the medulla cortex.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
gcm2Scer\UAS.cCa
gcm2UAS.cCa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Chotard
Secondary FlyBase IDs
    References (1)