Imprecise excision of the P{EP}grpEP587 insertion, resulting in a deletion that includes the first two coding exons of grp.
The mitotic checkpoint normally induced by 4000rad of irradiation is not detectable in grp209/grpZ5170 mutants. No checkpoint is detectable in these animals after irradiation with 500rad.
grp209/grpZ5170 males in which excision of insertions of P{hswa} is induced during development are completely viable.
E(mus304)[+]/PolA1Emus304, grp209/grpZ5170 has visible | male limited phenotype
E(mus304)[+]/PolA1Emus304, grp209/grpZ5170 has eye | male limited phenotype
grp209/grpZ5170 ; DNApol-α180Emus304/+ males have a rough eye phenotype, while grp209/grpZ5170 ; DNApol-α180Emus304/+ females have wild-type eyes. The wing discs of these mutant animals show an increase in apoptosis compared to wild type.