FlyBase Allele Report: Dmel\tal[unspecified]

General Information

Symbol

Dmel\tal^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0198103

Feature type

allele

Associated gene

tal

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

cephalopharyngeal skeleton

(Galindo et al., 2007)

denticle

(Galindo et al., 2007)

posterior spiracle primordium

(Galindo et al., 2007)

tracheal branch primordium

(Galindo et al., 2007)

ventral denticle belt

(Galindo et al., 2007)

Detailed Description

Statement

Reference

tal^unspecified embryonic mutant phenotypes include broken trachea, loss of cephalopharyngeal skeleton, abnormal posterior spiracles, and lack of denticle belts.

tal^unspecified mutants do not show any segmentation or homeotic phenotype. Although the mutant epidermis lacks denticle belts, segment-specific epidermal sensory organs are present, and segments are formed.

tal^unspecified mutant embryonic cells do not undergo the tubulin accumulation and cell morphology changes leading to the differentiation of denticles.

pri^unspecified embryonic mutant phenotypes include broken trachea, loss of cephalopharyngeal skeleton, abnormal posterior spiracles, and lack of denticle belts.

pri^unspecified mutants do not show any segmentation or homeotic phenotype. Although the mutant epidermis lacks denticle belts, segment-specific epidermal sensory organs are present, and segments are formed.

pri^unspecified mutant embryonic cells do not undergo the tubulin accumulation and cell morphology changes leading to the differentiation of denticles.

(Galindo et al., 2007)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

tal^unspecified is a suppressor of ventral denticle belt | ectopic phenotype of Scer\GAL4^wg.PM, ovo^UAS.svb.GFP

(Kondo et al., 2010)

NOT Suppressor of

Statement

Reference

tal^unspecified is a non-suppressor of ventral denticle belt | ectopic phenotype of Scer\GAL4^wg.PM, ovo^UAS.B.GFP

(Kondo et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of ovo^{Scer\UAS.T:Avic\GFP.svb} in the embryonic epidermis driven by Scer\GAL4^wg.PM in a tal^unspecified mutant background fails to induce ectopic ventral trichomes.

The ectopic embryonic ventral trichome phenotype resulting from the expression of ovo^{Scer\UAS.T:Avic\GFP.B} via Scer\GAL4^wg.PM is insensitive to the presence or absence of tal^unspecified mutant genetic background.

(Kondo et al., 2010)

Xenogenetic Interactions

Statement

Reference

Expression of Bmor\tal-like^Scer\UAS.cGa under the control of Scer\GAL4^unspecified rescues the tal^unspecified phenotypes in the adult and the embryo.

Expression of Bmor\tal-like^Scer\UAS.fl under the control of Scer\GAL4^unspecified rescues the pri^unspecified phenotypes in the adult and the embryo.

(Galindo et al., 2007)

Complementation and Rescue Data

Rescued by

tal^unspecified is rescued by tal^AB.UAS/Scer\GAL4^unspecified

(Galindo et al., 2007)

tal^unspecified is rescued by Scer\GAL4^unspecified/tal^NoB.UAS