UASt regulatory sequences drive expression of an inverted repeat.
Expressing Sf3b2GD11027 under the control of Scer\GAL4Act88F.PU leads to pharate indirect flight muscles with strong actin inclusions at Z-discs (so called Zebra bodies) and long filamentous actin extensions.
Adults expressing CG3605GD11027 under the control of the cardioblast-specific Scer\GAL4tin.CΔ4 driver show significantly reduced survival on day 6 after a shift to 29[o]C compared to control flies.
Adults expressing CG3605GD11027 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Expression of CG3605GD11027 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) results in viable flies or partial lethality, depending on the particular P{GD11027} insertion line used.
Expression under the control of Scer\GAL4Mef2.PR results in early larval lethality.
Expression under the control of Scer\GAL4Mef2.PR results in grossly normal larval body wall muscles.
Expression under the control of Scer\GAL4Mef2.PR results in sarcomeres with reduced Z-lines in the larval body wall muscles.
Expression under the control of Scer\GAL4pnr-MD237 results in lethality (either before or at the pupal stage), depending on the insertion line used.