UASt regulatory sequences drive expression of an inverted repeat.
Expression of Nsun5GD3061 under the control of Scer\GAL4Act5C.PU in males flies results in an increase in mean lifespan compared to controls. This increase in lifespan is not seen if the flies are maintained on a high nutrient diet.
Flies expressing Nsun5GD3061 under the control of Scer\GAL4Act5C.PU show significantly increased survival compared to controls when subjected to a 4 hour heat shock of 37[o]C.
Adults expressing Nsun5GD3061 under the control of the cardioblast-specific Scer\GAL4tin.CΔ4 driver show significantly reduced survival on day 6 after a shift to 29[o]C compared to control flies.
Adults expressing Nsun5GD3061 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.