UASt regulatory sequences drive expression of an inverted repeat.
Flies expressing drprGD14423 under the control of either Scer\GAL4repo.PU or Scer\GAL4elav-C155 do not show locomotor defects.
40 day old flies expressing drprGD14423 under the control of Scer\GAL4Act5C.PI sometimes show defects in the jump muscle of the thorax. Degeneration is also seen in the brain.
Adults expressing drprGD14423 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.