UASt regulatory sequences drive expression of an inverted repeat.
Expressing smoGD577 under the control of Scer\GAL4ey.PH does not cause any overt eye overgrowth.
Adults expressing smoGD577 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Expression under the control of Scer\GAL4Mef2.PR results in defects in wing posture.
smoGD577 enhances the eye overgrowth phenotype seen when DlScer\UAS.cDa is expressed under the control of Scer\GAL4ey.PH. Approximately 80% of flies exhibit eye overgrowth.