UASt regulatory sequences drive expression of an inverted repeat.
Very few progeny are seen when RpS15AaGD8827 is expressed in the heart under the control of Scer\GAL4tin.CΔ4. The flies that escape lethality show severely impaired heart function, with a decreased fractional shortening compared to controls.
Ubiquitous expression of RpS15AaGD8827 under the control of Scer\GAL4Act5C.PU results in lethality during development.
Expressing RpS15AaGD8827 in the adult heart using Scer\GAL4tin.CΔ4 (restricted to adult stages using Scer\GAL80ts.αTub84B) results in abnormal heart size and reduced cardiac function compared to controls.
Adults expressing RpS15AaGD8827 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.
Expression under the control of Scer\GAL4Mef2.PR results in early larval lethality.
Expression under the control of Scer\GAL4Mef2.PR results in split larval body wall muscles.
Expression under the control of Scer\GAL4Mef2.PR results in sarcomeres with reduced Z-lines in the larval body wall muscles.
Expression under the control of Scer\GAL4pnr-MD237 results in lethality before the pupal stage.