FlyBase Allele Report: Dmel\qvr[Δ40]

General Information

Symbol

Dmel\qvr^Δ40

Species

D. melanogaster

Name

FlyBase ID

FBal0218986

Feature type

allele

Associated gene

Dmel\qvr

Associated Insertion(s)

Carried in Construct

Also Known As

sss^Δ40, Δ40

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Koh et al., 2008)

Progenitor genotype

qvr^EY04063

(Koh et al., 2008)

Cytology

Description

Imprecise excision of the insertion in qvr^EY04063, resulting in a deletion that removes part of the qvr coding region.

(Koh et al., 2008)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal behavior

(Koh et al., 2008)

abnormal behavior (with qvr^EY04063)

(Koh et al., 2008)

decreased sleep | adult stage

(Vaccaro et al., 2020)

decreased sleep | adult stage (with qvr^EY04063)

(Zhou et al., 2023)

increased cell number | adult stage (with qvr^EY04063)

(Zhou et al., 2023)

increased rate of feeding behavior | adult stage (with qvr^EY04063)

(Zhou et al., 2023)

short lived

(Vaccaro et al., 2020)

Phenotype Manifest In

adult gut (with qvr^EY04063)

(Zhou et al., 2023)

intestinal stem cell | increased number (with qvr^EY04063)

(Zhou et al., 2023)

Detailed Description

Statement

Reference

qvr^Δ40/qvr^Δ40 and qvr^Δ40/qvr^EY04063 flies show a severely reduced amount of daily sleep compared to control flies.

(Koh et al., 2008)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

qvr^Δ40/qvr^EY04063 has decreased sleep | adult stage phenotype, suppressible by Gabat^PL00338

(Zhou et al., 2023)

qvr^Δ40/qvr^EY04063 has increased cell number | adult stage phenotype, suppressible by Gabat^PL00338

(Zhou et al., 2023)

Phenotype Manifest In

Suppressed by

Statement

Reference

qvr^Δ40/qvr^EY04063 has intestinal stem cell | increased number phenotype, suppressible by Gabat^PL00338

(Zhou et al., 2023)

qvr^Δ40/qvr^EY04063 has adult gut phenotype, suppressible | partially by Gabat^PL00338

(Zhou et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

qvr^EY04063

(Koh et al., 2008)

Rescued by

qvr^Δ40/qvr^EY04063 is rescued by qvr^UAS.cWa/Scer\GAL4^elav.PLu

(Zhou et al., 2023)

qvr^Δ40/qvr^EY04063 is rescued by qvr^UAS.cWa/Scer\GAL4^nSyb.PS

(Zhou et al., 2023)

qvr^Δ40/qvr^EY04063 is rescued by Scer\GAL4^Tub.PU/qvr^UAS.cWa

(Zhou et al., 2023)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

30865

w^*; qvr^Δ40/SM6a

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

(Koh et al., 2008)

qvr^Δ40

sss^Δ40

(Li et al., 2023, Zhou et al., 2023, Vaccaro et al., 2020, Wu et al., 2010)

sssΔ

(Chen et al., 2015)

Δ40

(Chen et al., 2015, Koh et al., 2008)

Δsss

(Chen et al., 2015)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

Open Close