FB2024_03 , released June 25, 2024
Allele: Dmel\dshsev.PU
Open Close
General Information
Symbol
Dmel\dshsev.PU
Species
D. melanogaster
Name
sevenless promoter construct of Unknown
FlyBase ID
FBal0219016
Feature type
allele
Associated gene
Dmel\dsh
Associated Insertion(s)
Carried in Construct
P{sev-dsh.U}
Also Known As
sev-dsh
Key Links
Transgenic product class
wild_type
(Rawls et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Rawls et al., 2007)
Mutagen
in vitro construct
(Rawls et al., 2007)
Progenitor genotype
Carried in construct
P{sev-dsh.U}
Cytology
Description

sev regulatory sequences drive expression of dsh.

(Rawls et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
sev
Encoded product / tool
dsh
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      dshsev.PU eyes are characterized by a loss of photoreceptors and planar cell polarity defects (including misorientated and symmetric ommatidia).

      (Serysheva et al., 2013)

      Mutants show defects in ommatidial polarity.

      (Rawls et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhanced by
      Statement
      Reference

      dshsev.PU has abnormal planar polarity phenotype, non-enhanceable by bdg164/bdg[+]

      (Rawls et al., 2007)
      NOT suppressed by
      Statement
      Reference

      dshsev.PU has abnormal planar polarity phenotype, non-suppressible by Scer\GAL4sev.PU/WnkKK102654

      (Serysheva et al., 2013)

      dshsev.PU has abnormal planar polarity phenotype, non-suppressible by Df(3L)ED4978/+

      (Serysheva et al., 2013)

      dshsev.PU has abnormal planar polarity phenotype, non-suppressible by Wnk[+]/WnkMB06499

      (Serysheva et al., 2013)

      dshsev.PU has abnormal planar polarity phenotype, non-suppressible by Wnk[+]/Wnkex22

      (Serysheva et al., 2013)

      dshsev.PU has abnormal planar polarity phenotype, non-suppressible by bdg164/bdg[+]

      (Rawls et al., 2007)
      Phenotype Manifest In
      NOT Enhanced by
      Statement
      Reference

      dshsev.PU has ommatidium phenotype, non-enhanceable by bdg164/bdg[+]

      (Rawls et al., 2007)
      Suppressed by
      Statement
      Reference

      dshsev.PU has eye photoreceptor cell phenotype, suppressible by Scer\GAL4sev.PU/WnkKK102654

      (Serysheva et al., 2013)

      dshsev.PU has eye photoreceptor cell phenotype, suppressible by Df(3L)ED4978/+

      (Serysheva et al., 2013)

      dshsev.PU has eye photoreceptor cell phenotype, suppressible by Wnk[+]/WnkMB06499

      (Serysheva et al., 2013)

      dshsev.PU has eye photoreceptor cell phenotype, suppressible by Wnk[+]/Wnkex22

      (Serysheva et al., 2013)
      NOT suppressed by
      Statement
      Reference

      dshsev.PU has ommatidium phenotype, non-suppressible by bdg164/bdg[+]

      (Rawls et al., 2007)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Scer\GAL4sev.PU-mediated expression of WnkKK102654 consistently suppresses the loss of photoreceptor phenotype but not the planar cell polarity phenotype of dshsev.PU eyes.

      Df(3L)ED4978/+ suppresses the loss of photoreceptor phenotype but not the planar cell polarity phenotype of dshsev.PU eyes.

      WnkMB06499/+ or Wnkex22/+ suppresses the loss of photoreceptor phenotype but not the planar cell polarity phenotype of dshsev.PU eyes.

      (Serysheva et al., 2013)

      The ommatidial polarity defects caused by dshsev.PU are not modified by one copy of bdg164.

      (Rawls et al., 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      dshsev.PU
      Name Synonyms
      sevenless promoter construct of Unknown
      sevenless promoter construct off Unknown
      Secondary FlyBase IDs
        References (3)