Amino acid replacement: S?A.
UASt regulatory sequences drive expression of a mutated form of numb, in which all of the 5 evolutionarily conserved aPKC phosphorylation sites are mutated from serine to alanine.
external sensory organ, with Scer\GAL4neur-P72
Expression of numb5A.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4neur-P72 results in cell-fate transformation in the bristle lineage.