FB2024_03 , released June 25, 2024
Allele: Dmel\faxKK102829
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General Information
Symbol
Dmel\faxKK102829
Species
D. melanogaster
Name
FlyBase ID
FBal0232035
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The adulthood-only expression of faxKK102829 under the combined control of Scer\GAL4C587 and Gal80[ts] leads to a progressive decrease in the number of germline stem cells in the germarium, but does not affect germarium size, the numbers of escort and cap cells, the proportion of germline stem cells undergoing cell division or the proportion of germline cysts presenting cells undergoing cell division, as compared to controls. This expression from the developmental stages onwards (i.e. in the absence of Gal80[ts] control) does not significantly affect the germline stem cells and cap cell numbers and only mildly affects the wrapping of germ cell cysts by escort cells, as compared to controls.

The escort cell within clones expressing faxKK102829 under the control of Scer\GAL4Act5C.PU show blunted extension of membrane processes that fail to completely wrap germ cell cysts, as compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
faxKK102829
Name Synonyms
Secondary FlyBase IDs
    References (2)