FlyBase Allele Report: Dmel\Tbcb[KK102880]

General Information

Symbol

Dmel\Tbcb^KK102880

Species

D. melanogaster

Name

FlyBase ID

FBal0232067

Feature type

allele

Associated gene

Dmel\Tbcb

Associated Insertion(s)

Carried in Construct

P{KK102880}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK102880}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK102880

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

partially lethal - majority live | pupal stage, with Scer\GAL4^da.G32

(Baffet et al., 2012)

partially lethal - majority live | pupal stage, with Scer\GAL4^en-e16E

(Baffet et al., 2012)

viable, with Scer\GAL4^ap-md544

(Baffet et al., 2012)

visible | adult stage, with Scer\GAL4^ap-md544

(Baffet et al., 2012)

visible | adult stage, with Scer\GAL4^da.G32

(Baffet et al., 2012)

visible | adult stage, with Scer\GAL4^en-e16E

(Baffet et al., 2012)

Phenotype Manifest In

wing, with Scer\GAL4^ap-md544

(Baffet et al., 2012)

wing, with Scer\GAL4^da.G32

(Baffet et al., 2012)

wing, with Scer\GAL4^en-e16E

(Baffet et al., 2012)

Detailed Description

Statement

Reference

When TBCB^KK102880 is expressed under the control of Scer\GAL4^da.G32, 91% of the flies that reach adulthood harbor altered wings.

When TBCB^KK102880 is expressed under the control of Scer\GAL4^en-e16E, 86% of the flies that reach adulthood harbor altered wings.

When TBCB^KK102880 is expressed under the control of Scer\GAL4^ap-md544, all of the flies that reach adulthood harbor altered wings.

Expressing TBCB^KK102880 under the control of either Scer\GAL4^en-e16E or Scer\GAL4^ap-md544 has no effect on cell proliferation in third instar larval wing discs.

(Baffet et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v103943

P{KK102880}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

CG11242^KK102880

TBCB^KK102880

Tbcb^KK102880

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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